Expression And Significance Of MAPK In Osteosarcoma

Objective Extracellular signal-activatedkinases(ERK), c-Jun N-terminal kinase(JNK) and P38 signal transduction pathway were three members of the MAPK family which mediated cellular proliferation, differentiation and apoptosis. The purpose of this study was to investigate the effects of ERK, JNK and P38 MAPK on pathogenesis and progression of human osteosarcomas . Methods...