A Study On Transfusion Transmitted Virus Co-infection In The Patients With Hepatitis C In Yanbian Area

Objective-. Transfusion transmitted virus (TTV) in hepatitis C patients in Yanbian area was detected for the co-infection frequency of TTV and hepatitis C in the patients. Methods: Enzyme linked immunosorbent assay and nested-Polymerase chain reaction were used to examine anti-TTV IgG and TTV DNA in the serum samples respectively. And above-mentioned two kinds of experiment methods will be compared. The levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in the serum samples were measured by using AutoBiochemistry Analyzer. Results: In the samples from 45 hepatitis C patients, the anti-TTV IgG positive rate was 37.8 % (17/45) while the TTV DNA positive rate was 42.2 % (19/45). ELISA and PCR were 86.7 % (39/45) to the unanimous rate of measuring that TTV infection. Conclusion: (1) TTV superinfection is common in the patients with hepatitis C. (2) ELISA and PCR are available as means to detect TTV. (3) It is the first time to adopt ELISA and PCR to submit a report on the condition of TTV co-infecting in the patients with hepatitis C in Yanbian area, and there is no statistical difference in the detection of TTV between the two methods.