Influence Of Different Operative Type Of Myoma Of Uterus On Female Hormones

Objective: To study the influence on the hormone level ofwomen with myoma of uterus after different operation of uterusand ovary, and to explore the most reasonable operative typesprovide basis for post-operation hormone replacement therapy.Methods: 80 female patients with myoma of uteruswere averagely divided into 4 groups according to the type ofoperation: groupâ… : 20 patients with hysteromyomectomy; groupâ…¡:20 patients with simple hysterectomy; groupâ…¢:20 patients withhysterectomy plus uni-lateral adnexctomy; groupâ…£:20 patientswith hysterectomy plus bilateral adnexectomy. The level ofFSH ,LH,E2 ,P,and T were detected respectively beforeoperation and in a week,8 weeks and 24 weeks after operation .Adopting the analyze system which named BECKMANCOUITER ACCESS ? made by USA. and BECKMAN reagent,measured the FSH ,LH,E2,P and T in serum by the method ofchemistry luminesce.Results: In groupâ… , the hormone level showed no statisticaldifferences at a week,8 weeks and 24 weeks after operationcompared with pre-operation (P>0.05).In group â…¡, the hormonelevels of FSH,LH,E2 ,P and T showed no statisticaldifferences at a week and 8 weeks after operation compared withpre-operation (P>0.05);the levels of FSH and LH increased butshowed no statistical differences at 24 weeks after operationcompared with pre-operation (P>0.05); and the level of E2declined and there were statistical differences at 24 weeks afteroperation compared with pre-operation (P<0.01); The levels of Pand T showed no statistical differences compared withpre-operation (P>0.05). In group â…¢, the hormone levels of FSH,LH ,P and T showed no statistical differences at a week andafter operation compared with pre-operation (P>0.05); the level ofE2 declined and there were statistical differences at a week afteroperation compared with pre-operation (P<0.05); the levels ofFSH and LH increased and the level of E2 declined and there werestatistical differences at 8 weeks and 24 weeks after operationcompared with pre-operation (P<0.01); The levels of P and Tshowed no statistical differences compared with pre-operation(P>0.05). In group â…£: the hormone levels of FSH,LH ,P and Tshowed no statistical differences at a week and after operationcompared with pre-operation (P>0.05);the level of E2 declined andthere were statistical differences at a week after operationcompared with pre-operation (P<0.01); the levels of FSH and LHincreased and the level of E2 declined and there were statisticaldifferences at 8 weeks and 24 weeks after operation comparedwith pre-operation (P<0.01); The levels of P and T declined butshowed no statistical differences at 8 weeks and 24 weeks afteroperation compared with pre-operation (P>0.05). Conclusion: In hysteromyomectomy, the uterine artery wasremained and the blood supply of ovaries was adequate. Theovaries had normal functions. So patients of hysteromyomectoryhad no influence on hormones. In hysterectomy with both-sideovary remaining, because of the damage of the integration inanatomy between ovary and uterus,the blood supply of ovarieswas reduced, and the function of ovary were influenced. Therefore,the levels of hormones were reduced. In hysterectomy with...