Expression Of KDR Protein In Ovarian Serous Carcinoma And Its Clinical Significance

Objective: To study the expression of KDR protein in ovarian serous carcinoma , and compare with normal ovary tissue to find their clinical significanceMethods: Western Blotting were used to detect the expression of KDR protein in 38 cases of ovarian serous carcinoma, 14 cases of ovarian borderline serous tumors, 11 cases of ovarian benign serous tumors and 10 cases of normal ovary tissues.Results: The positive rate (89.5%) and relative content(141. 10± 87.31) of KDR protein expression in ovarian serous carcinoma were statistically higher than that in ovarian borderline serous tumors (64.3%, 65.60 + 11.61) .The positive rate and relative content in ovarian serous carcinoma and ovarian borderline serous tumors were statistically higher than that in ovarian benign serous tumors (18. 2%,42. 62 ± 12. 66)and normal ovary tissues (10. 0% , 37.72 + 12.96).The positive rate and relative content of KDR protein expression in operative stage III+IV (96.2%, 181.96 + 96.37) were statistically higher than that in stage I+II (75. 0%, 112. 37 + 59. 28) . The positive rate and relative content of KDR protein expression in pathological grade III (95.5%, 171.76 + 91.66) were statistically...