| Objective : To determine the influence of Straight-Leg-Raisingmovement on epidural fibrosis after laminectomy. Methods:40 adult New Zealand rabbits were used as the laminectomymodel in the study. They were divided into 2 groups — —Straight-Leg-Raising group (SLR) and control group (C) randomly. Eachgroup had 20 animals. All of the rabbits were performed with totallaminectomy of S1. 5 rabbits of each group selected randomly were killedin the first, the second, the forth and the eighth week after laminectomy.The gross specimens were assessed by Rydell criteria. Scar areas weremeasured by American image-pro plus 4.5 analyzing processor. Themeasurement of fibroblasts and inflammatory cells: the same magnificationslice was selected (400×), then the number of the fibroblasts andinflammatory cells were measured by the mouse in the computer. Results:In the gross observation, the formation of scar in the SLRgroup was later than C group at the first two weeks, but there was nostatistical difference between the two groups in adhesion degree (p≥0.05);In the 4th and 8th week, the epidural fibrosis of the SLR group was moreserious than that of the C group. The scar area in SLR group was largerthan that of C group in week 2, 4 and 8. The count of fibroblasts andinflammatory cells in SLR group was bigger than that of C group in earlystage. But in lately stage, there was no statistics significant between the twogroups on the count of cells. Conclusions: Straight-Leg-Raising movement after laminectomymay aggravate the formation of epidural scar, and it may retard the maturityof scar. SLR movement also aggravate the adhesion of scar.
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