The Differentiation Of The Cerebral Blood Flows Before And After Mastication Of The Edentulous-jaws Patients With Complete Denture: A Controlled Study

The differentiation of the cerebral blood flows before and aftermastication of the edentulous-jaws patients with complete denture: Acontrolled studyPurpose: Our research is focus on the effects of masticatory movements on thefunction activity of brain via compare the blood flow variety before andafter restoration of edentulous jaws with complete denture.Materials and Methods:1. 20 Edentulous patients without malaise two month after restoration were selected. The flow-rate of brain blood flow was recorded at different intervals, which include insert denture without mastication, 5 min after mastication, 10 min after mastication, with TCD. The blood flow-rate was compared before and after mastication. Another 20 edentulous patients without dentition defect were used as control.2. The patients were asked to lie down. Doppler Ultrasound Scan was carried out after 30 min of rest. The middle cerebral artery(MCA) peak flow-rate in systole period(Vs), late diastole period(Vd) and mean peak flow rate(Vm) through temporal window under normal state. After first assay, the patients were asked to chew chewing gum for 5 min and 10 m, then, the Vs, Vd and Vm of MCA was measured. 4Results:1. For both the control group and the patient group: 1)The effects to Vs caused by mastication approach the level of obviousness(P=0.056). 2) The differences of Vm caused by mastication have the significance of obviousness(P<0.001). 3) During each period of the test, the averages of Vs and Vm of the control group all exceed the relating averages of the patient group. 4) The effects to Vd caused by mastication appear no obviousness(P=0.153).2. The element of repetition: there is obviousness(P<0.001) for the differences among the three levels of the element of time. As test time extends longer, the averages of Vs, Vd and Vm all reach higher levels.3. For the cases of five and ten minutes after the mastication, comparing with that before mastication, both the control group and patient group witness: The differences of Vs, Vd and Vm caused by mastication all have the significance of obviousness(P<0.001), which shows that the Vs,Vd and Vm of both groups after mastication are all higher than before mastication.Conclusions:1. MCA supplies less blood in edentulous patients compare with the control group.2. Mastication movements can enhance the supply of cerebrum. 5...