| Objective: To explore the indications of mini-invasive aspiration and thrombolysis forpatients with hypertensive ganglionic hemorrhage via the prognosis and therapeutic efficacy of various treatment groups.Methods: Of the inpatients with hypertensive ganglionic hemorrhage hospitalized at thefirst affiliated hospital of Jinan University, 119 cases were enrolled into our studies and were divided into three groups corresponding to their managements. For each case, general data, radiological and laboratory results were documented according to their case histories, and clinical global outcome were rated in light of their various sets of concerned criteria. Of patients with various levels of hemotoma volume and GCS score, the relationship of three kinds of therapeutic approaches to their efficacy was analyzed with SPSS 10.0 software.Results: Analysis of the 30th day Scandinavia Stroke Scale score showed a linear trendpositive to GCS score of 25~90ml hematoma volume and negative to hematoma volumeo There is no difference in the prognoses and therapeutic efficacy among the three treatment groups with hematomas of 25.0~ 39.9ml. The prognoses and therapeutic efficacy of aspiration and craniotomy groups was superior to that of the conservative one for the hematomas of 40~90ml. For the hematomas of 25~90ml and GCS score 8 points, the prognoses of aspiration group was superior to that of the conservative one, but there is no significant difference between the craniotomy and conservative groups; however, the therapeutic efficacy of aspiration and craniotomy groups was superior to that of the conservative one. For the hematomas of 25~90ml and GCS score 7 points, the prognoses of the craniotomy group was superior to that of the conservative one, but there was no significant difference between the aspiration and conservative groups; however, there is no significant difference in the therapeutic efficacy among the three groups.Conclusion: For patients with hypertensive intracerebral ganglionic hemorrhage of 25~ 90ml hematoma volume, the prognoses degenerate as hematomas expand and improve asthe GCS score increase. The patients with hematomas of 40 ~ 90ml is prone to the mini-invasive aspiration and thrombolysis for GCS score 8 points and is prone to craniotomy for GCS score 7 points. |