Cancer Patient During Perioperative And The Result Of Taking The No.1 Chinese Angelica Decoction For Replenishing Bolld

Objective To study the variety regulation of immune function of non-small cell lung cancer patient during perioperative ,and observe influence to immune function of NSCLC patient during perioperative by the No.l Chinese Angelica Decoction for Replenishing Bolld.Method T-lymphocte subsetshe were measured by indirect immunity fluorescence. The active of Natural killer cell second were measured by radioactive nuclide release . The serum levels of IgA, IgM, IgG were measured by single direction immunity diffuse. The serum levels of IL-2 and TNF- α were measured by enzyme-linked immunosorbent assay(ELISA) . The serum levels of CYFRA21-1 and CEA were measured by radioimmunoassay(RIA). And the general condition were evaluated. The software package of statistics SAS6.2 were applicated to proceed the statistics analysis.Result Cell and body liquid immune function of NSCLC were obviously turn down compared to the healthy people (P<0.05). the serum levels of IL-2 were obviously lower. but the serum levels of TNF- a was very high . the serum levels of CYFRA21-1 and CEA were also obviously go up.the statistically significant difference was found compared to the healthypeople ( P<0.05).In one week postoperation , immune function were further restrained. After three or four weeks ,the immune function of NSCLC can reach normal level.but the restrained of immune function postoperation of the group which taking NO.l Chinese Angelica Decoction for Replenishing Bolld during perioperative were obvious alleviated; After two weeks ,the immune function can reach the normal level and always maintain the good condition, the statistically significant difference was found compared to matched control( P<0.05). Conclusion1. Immune function of NSCLC was restrained by tumour.The degree of restrain has correlate with the TNM stage.The pathologic basic is tumor lump. After the excision of tumor, the immune function of NSCLC that has been restrained can comeback gradually.2. In one week postoperation, immune function were further restrained. Taking NO.l Chinese Angelica Decoction for Replenishing Bolld during perioperative, can obviously alleviate the degree of immune function restrained postoperation; it can exaltation the speed of recovery of immune function .strengthen immunity function. Benefit postoperation recover, increasing the living quality; strengthen patient's confidence.it has no effect to liver function and kidney function; during the process of experiment did not see the bad reaction.3. Dynamic monitor the immune function and tumor marking of NSCLC, can be used as the judgment index of NSCLC patient's illness condition and treatment result.