| [Background] Coronary artery calcification(CAC) is an important characteristic of coronary heart disease(CHD), which is also an earlier sign of atherosclerosis. So it is great valuable to diagnose subclinical coronary heart disease that CAC is detected exactly in its earlier period. Electron beam computed tomography (EBCT) is an accurate and non-invasive equipment that can detect and analyze CAC quantatively. EBCT can predict coronary artery disease earlier and identify high risk population by reflecting atherosclerosis burden exactly, so effective measures can be given to patients earlier. In this study, relationship between CHD risk factors and CAC detected by EBCT were evaluated, and the value of ECG UCG and EBCT in coronary heart disease diagnosis were analyzed.Study I A study on correlation between CHD risk factors and CAC detected by EBCT[Objective] To study the value of CAC detected by EBCT inearlier CHD prediction by analyzing the correlation between CAC and risk factors of CHD.[Methods] 445 cases detected by EBCT scanner were grouped according to age, sex, family history, hypertension, hyperlipidemia, diabetes, tobacco smoking, obesity and homocysteine. The differences among the groups were compared and analyzed statistically.[Results] (1) The coronary calcification incidence (CACI) of male and female were 46.3% and 31.5% respectively, which were not significantly different (P>0.05); Coronary artery calcification score (CACS) of male and female were 0(9) and 0(3) respectively, which were significantly different (P<0. 05).(2) The CACI of <60, 60-80 and 80 years old groups were 36%, 63.5% and 100% respectively, the CACS were 0(2), 131(365.1) and 658.5(833) respectively, which were significantly different(P<0. 001).(3) The CACI of the groups with or without family history were 44.1% and 41.7% respectively, the CACS were 0(9) and 0(6.7) respectively, which were not significantly different (P>0. 05).(4) The CACI of the groups with or without hypertension were 52.2% and 37.3% respectively, the CACS were 1(28) and 0(3) respectively, which were significantly different (P<0. 001).(5) The CACI of the groups with or without hyperlipidemia were 62% and 31. 6% respectively, the CACS were 3 (84) and 0 (2) respectively, which were significantly different(P<0.001).(6) The CACI of the groups with or without diabetes were 79.5% and 35.5% respectively, the CACS were 45(193.8) and 0(9) respectively, which were significantly different (P<0. 001).(7) The CACI of the groups with or without tobacco smoking were 48. 9% and 38. 5% respectively, the CACS were 0(20. 6) and 0(4) respectively, which were significantly different (P<0.05).(8) The CACI of the groups with or without obesity were 45. 9% and 34.9% respectively, the CACS were 0(10) and 0(9) respectively, which were significantly different (P<0. 05).(9) The CACI of the groups with or without homocysteine were 50% and 22.2% respectively, the CACS were 0.5(42.8) and 0(1.2) respectively, which were not significantly different (P>0. 05).(10) The CACI of the groups from 0 to six risk factors of coronary heart disease were 16.8%, 25.3%, 41.6%, 42.6%, 55.9%, 79. 5% and 100% respectively, the CACS were 0(0), 0(1), 0(6.5), 0(4. 3), 1(29. 9), 35(218. 7) and 604.5(952.0) respectively, which were significantly different (P<0. 001).[Conclusion] Although correlations were not found between CAC detected by EBCT and some risk factors of CHD, such as family history and homocysteine, there were close correlations between CAC and other risk factors, such as sex, age, hypertension, hyperlipidemia, diabetes, tobacco smoking, obesity, and the number of risk factors, which means that CAChas very important clinical value in CHD earlier prediction.Study II The Value of EBCT, ECG, UCG and Co-application in Coronary Artery Disease Diagnosis[Objective] To evaluate the value of EBCT, electrocardio-graghy(ECG), ultrasound cardiogram(UCG) and Co-application in Coronary Artery Disease Diagnosis.[Methods] The corre...
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