Initial Research On Coronary Artery Calcification Of The Village Population In Yunnan Province

Objectives To initially evaluate coronary artery calcium (CAC) and coronary arterycalcium score (CACS) characteristics of the village population in Yunnan province.providing the baseline data for CAC evolution and risk stratification of coronaryheart disease prevention study．To evaluate the association between CAC and theconventional risk factors of coronary heart disease (CHD)in the village population ofYunnan province．Materials and methods Eleven villages were randomly selected from Yunnanprovince, yongping,yongsheng,liming and weixi country, from which a total of840randomly selected subjects from7ethnic minorities and the Han ethnic majorityparticipated in a cross-sectional survey, From each village,35-45men and womenbetween the age of51and71years were randomly selected. Exclusion have doneperm pacemaker placement operation and heart intervention operation patients.All subjects underwent coronary calcium scan with Philips16Multi-detectorComputed Tomography(16-MDCT) in the Affiliated Hospital of Dali College fromJuly,2012to December,2012.CACSof each subject was calculated． Thecharacteristics and difference of CAC and CACS was compared between groups ofgender,age and race．Standard question are of conventional cardiovascular diseaserisk factors， blood pressure,height, weight, cholesterol, high-density lipoproteincholesterol and creatinin examination of each subject was also obtained．Multivariablelogistic and1inear regressions were used to determine the cross-sectional associationof risk factors with positive CAC and CACS [(CACS transformed into naturallogarithm (1n)(CACS+1)].Results①T he positive rate of CAC in174sample was22.4％and39sample with CACS≥1,the positive rate of CAC51-60years group and61-71years group was15.5％,34.4％respectively and the CACS was11.2±52.4,38.0±82.0. the differenceof CAC and CACS in these groups had statistical significance (P <0.05), but theseindex between the gender and race had not statistical significance,②total calcium score（TCS）was21.1±66, the CACS of1eft main(LM),the1eftanterior descending artery (LAD),1eft circumflex artery (LCX) and right coronaryartery was0，11.3±49.8，3.2±20.5and5.9±29.0respectively. and the positive rate ofCAC was0，14.9％、7.4%and6.9％respectively， the highest incidence of CAC incoronary artery was LAD, followed by LCX and RCA, the lowest incidence of CACwas LM.③T he independent risk factors of CAC was age(odd ratio was3.314，p<0.05)，Theindependent risk factors of CACS were age and hyperlipidemia(Standard regressioncoefficient was0.266,0.178respectively，p<0.05).Conclusion CAC and CACS exist age differences in age group of51-71years inthe village population in Yunnan province. age is the independent risk factors ofCAC.The highest incidence of CAC in LAD, followed by LCX and RCA. The CACand CACS in the population of Yunnan province village detected by16-MDCT isassociated with conventional cardiovascular disease risk factors. The presence andextent of coronary artery atherosclerosis in the population can be predicted byconventional risk factors.0f a11the factors, age and hyperlipidemia is the best twopredictors for the presence of coronary artery atherosclerosis．...