Clinical Study Of Doppler Ultrasound In Differentiation Of Breast Neoplasms

Purpose. In this study , the quality of the breast neoplasms were assessed by two-dimensional ultrasound , color Doppler ultrasound and power Doppler ultrasound. The aim is to evaluate the clinical value of Doppler ultrasound in differentiation of breast neoplasms. Materials and methods. Sixty consecutive patients with breast neoplasms were prospectively assessed by ultrasound before operation. All were tested by pathology. Thirty of them were benign , the others were malignant. First, the nature of breast neoplasms were evaluated by two-dimensional ultrasound. Second, the features of blood flow in neoplasms were evaluated by color Doppler ultrasound. Meanwhile, the peak systolic velocity (PSV), resistive index (RI) and pulsed index (PI) were recorded by pulsed Doppler spectrum. Finally, the types of the blood flow in neoplasms were evaluated by power Doppler ultrasound.Computer-assisted analyzed color pixel density (CPD) of breast neoplasms. Results. The boundary, capsule, bilateral shadow, internal echo, back echo, backward echo, histology invasion and longitudinal-transverse ratio of breast neoplasms had significance (p<0. 01). Vessels were detected in 29 of 30 malignant vs 25 of 30 benign (p>0. 05) . Color signals were scored as 0~ I in 19 of 30 benign (63.34%) and as II -III in 27 of 30 malignant (90%). The difference between two groups was significant (p<0. 01). By the test of Doppler flow spectrum, PSV had no significance. There was significant difference if RI O. 7 or/and PI 1. 1 is statistically regarded as a criterion for the differentiation of breast neoplasms. Power Doppler signals were typed as I~II in 20 of 30 benign (70%) and as HI- IV in 29 of 30 malignant (96.67%). The PDI by computer-assisted analysis had significance. There was significant difference if CPD ^ 21% is statistically regarded as a criterion for the differentiation of breast neoplasms. With the standard of two-dimensional ultrasound, the differentially diagnostic sensitivity, specificity and accuracy for breast neoplasms were 96. 7%, 60% and78. 3%. With the standard of color Doppler ultrasound, the differentially diagnostic sensitivity, specificity and accuracy were 86.7%, 70% and 78. 3%. With the standard of power Doppler ultrasound, the differentially diagnostic sensitivity, specificity and accuracy were 86.7%, 76.7% and 81.6%. Integrating with three methods, the differentially diagnostic sensitivity, specificity and accuracy were 93. 3%, 83.3% and 88.4%. Comparing with two-dimensional ultrasound and combination of three methods , the specificity had significant difference (p<0. 02) , the sensitivity and accuracy had not difference (p>0. 05). Conclusion . In this study, two-dimensional ultrasound integrating with color Doppler ultrasound and power Doppler ultrasound differently diagnose the breast neoplasm. The specifity was greatly improved . So, it had much clinical valuable in improving the accuracy of diagnosing the breast neoplasms and decreasing the rate of misdiagnosing the breast neoplasms.