| Object:1.In order to explore the probable value of AMM and QTVI on CAD,we observe the feature of myocardial motion in normal subjects and patients with CAD.2.we sought to clarify whether QTVI could be used as an noninvasion method to evaluate the effect of revascularization including coronary stenting and CABG . Methods: With vivid 7 echocardiographic instrument by a 1.5-4.0MHz transducer,twenty five normal people average 42-73 years old and thirty-one patients with CAD average 39-82 years old confirmed by coronary angiography were involved in the observation. The ventricular segmental wall thickness and amplitude were measured by Anatomic M-mode echocardiography in all subjects.Then we got the ventricular wall thickening fractions .The velocity(Vs ,Ve and Va)of left ventricular wall and mitral annular were measured by QTVI in all subjects before and after coronary-stenting or CABG from the apical four-chamber view ,the apical two-chamber view and the apical long axis view of the left heart.Results:1.In the normal subjects,the ventricular segmental wall amplitude was 7-10mm,and the ventricular wall thickening fractions was 25%-50% but in CAD groups,the abnormal ventricular segmental wall amplitude was 4-8mm and the ventricular wall thickening fractions was 0%--40%,which was coherent to the distribution of coronary artery . In the normal groups,their QTVI curve( Vs ,Ve and Va )were clear,and there were some regularities of the left ventricular segmental. The grads of the velocity in normal group were obvious. But in the CAD group,the decrease of the velocity and changes of their curve wave were obvious and their QTVI curves( Vs ,Ve and Va )were illegible and their normal patterns were lost. 2.In coronary stenting groups ,the Vs of the recovery segments perfused by LAD,RCA and LCX were improved significantly ,especially in AW (P<0.01),IW(P<0.001)and LW(P<0.05)as well as in mitral annular(P<0.001 in AW,IW and LW).In CABG group,the Vs of of the recovery segments perfused by LAD were improved significantly in AW(P<0.05)and in AS(P<0.05),in the same as, the Vs of mitral annular were improved significantly(P<0.05,P<0.001).Conclusion:1.AMM could be an effective method on evaluation the abnormal motion of regional wall motion of left ventricle and the sensitivity and specificity of AMM on evaluation the abnormal motion of regional wall motion of left ventricle of CAD are 80.64% and 88.23%.2.The velocity of ventricular segmental measured by QTVI can reflect the regional systolic function in CAD and the sensitivity and specificity of QTVI on evaluation abnormal motion of regional wall motion of left ventricle of CAD are 96.77% and 94.12%.3.The change of the velocity of ventricular segmental measured by QTVI after coronary revascularization can reflect the effect of coronary stenting or CABG.QTVI is an effective method on evaluation the effect after revascularization and it is worth using widely. |
