| Objective: To observe the effects on treating the middle-late lung cancer with Fei Yiliu Mixture after chemotherapy. Methods: 78 confirmed primary lung cancer patients were randomly divided into two groups. 42 patients of the treated group were treated with Fei Yiliu mixture and chemotherapy. 36 patients in control group were treated with chemotherapy, and the clinical therapeutic effects were observed. In the mouse experimental study, we observed the two group's effect of treating the mouse model of lung cancer with Fei Yiliu mixture, Fei Yiliu mixture plus the chemotherapy and their S180. Results: The clinical study showed the therapeutic effects of the treated group were more significant than it of the control group (P<0.05 or P<0.01). We also found the immune index increased and the toxic reaction caused by the chemotherapy reduced significantly in treated group. The animal experiment showed the same results as it shown in the clinical study in the inhibiting tumor. Fei Yiliu mixture also cooperation effect with cyclophosphamide in inhibiting tumor. Conclusion: Fei Yiliu mixture plus chemotherapy has better effects on inhibiting tumor than chemotherapy does. And Fei Yiliu mixture can reduce the toxic reaction caused by the chemotherapy.
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