The Study On The Cell Cycle Of Exfoliative Cells Of The Yellowish And Greasy Fur Of Tongue Of The Chronic Superficial Gastritis Wish Spleen-Stomach Damp-Heat Syndrome And The Effect Of Qing Huayin

Objective: To study on the cell cycle of exfoliative cells of the yellowish and greasy fur of tongue and the change of cell cycle and the clearance of the yellowish and greasy fur after Qing huayin's teatment.Methods: 66 patients were examined by pathology for the Chronic Superficial Gastritis (CSG) selected as research subjects. According to the syndromes of CSG of Chinese medincine. 39 cases belonged to spleen-stomach damp-heat (SSDH) syndrom with the yellowish and greasy fur group, 27 cases belonged to spleen-stomach qi vacuity(SSQV) syndrome with the thin and whitish fur group. 16 healthy persons as control group with the thin and whitish fur(all for the volunteer). All of them had been checked by gastroscope. 21 cases belonged to SSDH syndrome were treated by Qing huayin(QHY) 30 days to observe the clearance of the yellowish and greasy fur. The percentages of each phase in the cell cycle and the apoptotic cells of the exfoliative cells of tongue in four groups(control group 16 caseses, SSDH syndrome group 39 caseses, SSQV syndrome group 27 caseses, the SSDH syndrome treated with QHY group 21 cases) were measured by the Flow cytometer( FCM).Results: 1 .The symptoms of yellowish and greasy fur of tongue and so on in SSDH syndromes group were improved, which compared with before treatment, all had very significant difference( P<0.01). The total effective rate was 92.4%.2. The percentages of each phase in the cell cycle of the exfoliative cells of tongue in the control group with the thin and whitish fur compared with other three groups indicated that, the percentage of the SSDH syndrome with the yellowish and greasy fur group 's G1 phasecells was significantly lower and S phase cells was significantly higher than that of the control group with the thin and whitish fur and the SSQV syndrome with the thin and whitish fur group, and the SSQV syndrome group's S phase cells was higher than the control group's ,and all had significant difference( P<0.01, P<0.05, P<0.01).3.After treated with QHY 30 days of SSDH with the yellowish and greasy fur group, the percentage of S phase cells decreased, and the percentage of G1 phase cells and G2+ M phase cells increased and had significant difference as compared with before treatment( P<0.05 P<0.05).4.The percentage of the apoptotic cells in the SSQV syndrome with the thin and whitish fur group and the SSDH syndrome with the yellowish and greasy fur group were higher than that of the control group with the thin and whitish fur, and the SSDH syndrome group's was lower than the SSQV syndrome group's, and all had very significant difference(P