| Objective: The cancer is a type of grave disease which is intimidation to mankind's health and harm the people's existence. The chemotherapy is the significant means to treating the cancer, yet the obvious by-effect is disgusting,vomiting. This causes the limit of chemotherapy medicines' extensive using. Contemporary medical treat vomiting with 5-HT receptor antagonist. Although the effect is more ideal, it still has some disadvantage. Therefore we ought to bring into play the traditional Chinese medicine preponderance. we unite the contemporary medical' mechanism about vomiting caused by chemotherapy and bring about the mechanism that is "fire strongly fragrant" in the angle of traditional Chinese medicine theory, and treat it by the method of qingrexiehuo The antiemetic capsule of liansu is the classic way on the basic of this theory. By means of the effect of the antiemetic capsule of liansu on the pigeon' vomiting due to chemotherapy, we try to discuss the mechanism through nerve media, verify the method of qingrexiehuo' effect on the vomiting due to chemotherapy. This shall rich the traditional Chinese medicine theory, and have a importance function on explore traditional Chinese medicine which haveperfectly curative effect on vomiting due to chemotherapy.Means: 1.The effect of the antiemetic capsule of liansu on the dog's vomiting due to L-dopa:The concrete means is:Get 32 health dog, randomly separate into 4 series, Per series has 8,act as separately the pattern comparison series, the low dosing series of antiemetic capsule of Liansu (0.276 raw medicine/kg), the high dosing series of antiemetic capsule of Liansu (0.552g raw medicine/kg), and the masculine series of Ondanstron (0.67mg/kg). Different series of animal all starve 24 hours before the experiment. The medicine series once swallow the medicines. The pattern comparison group swallows equal amylum, 3h latter different series of animal swallow L-dopa(80mg/kg, immediate start up stopwatch, writing down the time which per dog has started to vomiting (vomiting latent period)and the vomiting times in 2 hours after swallowing L-dopa. Compare the differences among all the serious in T Examination. 2.The mend of the pigeon vomiting model caused by platinum: means:First step: Sets up multi-dose series(20mg·kg-1,16mg·kg-1,8mg·kg-1,4mg·kg-1,3mg·kg-1), Per series has 10 pigeon, avoirdupois 450-520g.Every other 24h time inject platinum once. Let the pigeon liberally to drink grape sugar of 10% so as to maintain nourishment after injecting, Moreover watch the situation of vomiting in 8h.Second step:The abdominal cavity is injected with platinum, Successive 3 days, With 4-4-3mg ·Kg-1's dose is tested. Third step:The abdominalcavity is injected with platinum Successive 3 days, With 4-3-3mg ·Kg-1's dose is tested.3.The antiemetic capsule of liansu' effect on the vomiting times, nerve media, and the duodenum pathological of the pigeon caused by platinum:Means:rear the pigeon normality one week, note their activity, take food, stool and so on, Afterwards randomly divided into 5 series: The blank comparison series, the pattern comparison series, the masculine medicine Ondanstron serious(1.93mg/kg),the low dosing series of antiemetic capsule of Liansu (360mg raw medicine/kg), the high dosing series of antiemetic capsule of Liansu(720mg raw medicine /kg).Per series has 10pigeon. All the medicine serious give medicine by stomach, the capacity is 4ml/kg, the blank comparison series, the low dosing series of antiemetic capsule of Liansu, the high dosing series of antiemetic capsule of Liansu were given the medicine 3 days ahead of time, the masculine medicine comparison series was given the medicine 1 day ahead of time. The pattern comparison series, the masculine medicine comparison series, the low dosing series of antiemetic capsule of Liansu, the high dosing series of antiemetic capsule of Liansu all offers with platinum, abdominal cavity is injected, The amount was 4mg/kg 1st day,2nd day in the amount of 3mg/kg,3rd d...
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