| Objective: To study the relative factors on delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) such as age,sex,occupation,history of cardiovascular or cerebralvasculor disease,coma lasting time,treatment time with hyperbaric oxygen ,poisoing degree and the significance of CT and BEAM,and explore the corellation between these relativ factors and DEACMP, comprehend the role of hyperbaric oxygen treatment in inhibiting and decreasing the DEACMP and the applied value of CT and BEAM for judging the severity and forecasting the occurrence of DEACMP . Methods: 1. Clinical relative factors, seven relative factors such as age,sex,occupation,history of cardiovascular or cerebralvasculor disease,coma lasting time,treatment time with hyperbaric oxygen ,poisoing degree were analysed between 36 patients with DEACMP(DEACMP group) and 40 patients with acute CO poisoing but without DEACMP(Control group).2. CT, use the CT machine of SOMATOM ＡR NOVA CT , scanning matrix 256×256and scanning thick 10mm , taking plain scain of head transection.22 patients of DEACMP group and 26 patients of control group had received the CT inspection during two weeks after hospitalization and these patients were divided into three groups of mild ,moderate ,severe degree according to the poisoing degree and analysed the correlation between significance of CT and different poisoing degree. 3. BEAM ,Use the BEAM machine of BA-III of American biological logic company and place the electrode according to international 10/20 systerm . use unipolar lead tracing and collect the tipical EEG example to do the BA analyzing and show the mapping of different frequency zone by the computer. 33 patients of DEACMP group and 30 patients of control group had received the BEAM inspection during 48 hour after acute carbon monoxide poisoning and analysed the correlation between significance of BEAM and different poisoing degree.Results: 1. The study of the clinical relativ factors of the DEACMP group and control group showed that there was extremely significant difference in coma lasting time (P<0.01)and that there was marked difference in the age,history of cardiovascular or cerebralvasculor disease,treatment time with hyperbaric oxygen (P<0.05).there was not marked difference in sex,occupation (P>0.05)(table 1).there was the correlation between poisoing degree and the incidence of the delayed encephalopathy(table 2). theincidence of mild group is 13.89%, the incidence of moderate group is 27.28%, the incidence of severe group is 58.33%. 21 patients(77.78%) of severe group developed the delayed encephalopathy. The poisoing degree is greater , the incidence of the delayed encephalopathy is higher. 2. CT showed that there were low density changes in the cerebral white matter,basal ganglar or globus pallidus of tow sides(table 3). The abnormal rate of CT is 56.25%. The abnormal rate of CT in the DEACMP group is 77.27%, The abnormal rate of CT in the control group is 38.46%, there was marked difference between two group(P<0.05).Moreover, there was parallel relation between the abnormal rate of CT and poisoing degree (table 4). The abnormal rate of CT in mild group is 20% , The abnormal rate of CT in moderate group is 43.48%, The abnormal rate of CT in severe group is 84.85%. 3. The abnormal rate of BEAM is 63.49%. The abnormal rate of BEAM in the DEACMP group is 84.85%, The abnormal rate of BEAM in the control group is 38.46%, there was marked difference between two groups(P<0.05)(table 5). there was significantly parallel relation between the abnormal rate of BEAM and poisoing degree(table 6) . The abnormal rate of BEAM in mild group is 23.81% , The abnormal rate of BEAM in moderate group is 72.73%, The abnormal rate of BEAM in severe group is 95%. The abnormal appearance was that the power was high in the θ,δzone and the powerwas low in the αzone. The abnormal range is forehead and temporal regine.Conclusion: 1. long lasting coma,eldly,previously with cardiovascular and ce... |
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