| Objective To elucidate the relationship between the concentration of Calcium and Magnesium in serum and acute cerebral infarction and its clinical significance. Methods The concentration of Calcium and Magnesium in serum individually at onset and at 2 weeks after the onset was determined in 75 patients who were diagnosed definitely as acute cerebral infarction, the concentration of Calcium and Magnesium in serum was determined in 63 senile people(control group), the clinical nerve deficiency scale was calculated in every patient, according to the results of clinical nerve deficiency scale, the patients were divided into mild cerebral infarction, moderate cerebral infarction and severe cerebral infarction. Results Compared with the control group, the concentration of Calcium and Magnesium in serum of patients was significantly lower (P<0.01), the concentration of Calcium and Magnesium in serum of mild cerebral infarction patients, moderate cerebral infarction patients and severe cerebral infarction patients was also distinctively different, the concentration of Calcium andMagnesium in serum of patients at the end of the second week was increased than that at onset (P<0.01) , but compared with the control group, it was lower (P0.01) . Conclusion The concentration of Calcium and Magnesium in serum of acute cerebral infarction is decreased, the degree of decrease was correlated with the clinical nerve deficiency scale, the concentration of Calcium and Magnesium in serum increased with the patients' recovery.
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