| Ventricular septum Defect (VSD) is the most common left-to-right shunt Congenital Heart Disease (CHD). While Tetralogy of Fallot is the most common right-to-left shunt cyanosis one. It is very important clinical significance to accurately evaluate the left ventricular function. The M-mode echocardiography can be used to evaluate left ventricular systolic function. But it is difficulty in measuring when Ventricular septal and the left ventricular posterior Wall are dyskinesia, its accuracy is also affected by the abnormal dissecting structure of heart. The Pulse wave Doppler Echocardiography (PWDE) assesses mitral inflow velocity can be used to evaluate left ventricular diastolic function, but is easily affected by heart rate ^reatlu heart load and so on. Cardiac catheterization is considered to be "Golden standard". However, because of its invasive, it can't be launched generally. TissueVelocity Imaging (TVI) is an important development of Doppler Echocardiography technology in recent years. It is used to assess mitral annular velocity and myocardial Wall motion velocity. Also, as a new method of evaluating heart function, it was extensively used to evaluated heart function of adult. But TVI used for children with CHD has not been reported in china. The purpose of this article to determine the systolic velocity(s), early-diastolic velocity (e), and late-diastolic velocity (a) of mitral valve annulus of normal children and children With VSD and TOP using TVI, is to evaluate the left ventricular function of VSD and TOP, compare M-mode Echocardiography and PWD Echocardiography (PWDE) and probe the change of left ventricular systolic and diastolic function in children with CHD using TVI so as to look for a effective and sensitive new way of evaluating children's heart function in clinical diagnosis and treatment.MethodBased on the ratio of VSD t /AO, 87 cases in VSD group are divided into three groups: the small VSD group(VSDs) > the moderate VSD group (VSDM), the large VSD groupCVSOJ and VSD with pulmonary hypertension group (VSD+PH). Based on the ratio of PA/AO, 41 cases in TOP group are divided into three groups: mild TC^ moderate TOP and severe TOP 86 cases in normal children group. We measure Left ventricular Ejection Fraction (LVEF) using M-mode Echocardiography. Mitral inflow velocity E.% A and ventricular septum Defect shunt peak Velocity (VSDPV) using PWDE and SN e, a using TVI, respectively. Mean while record 3 to 5 electrocardiogram cycle, take the average and measure the blood pressure of rightupper limb of children with VSD. Variance analysis is used for VSD group and normal group. Matching test is used for TOP group and normal matching group. Matching-enumeration data chi-square test is used to compare TVI e/a and PWD E/A. Linear regression analysis is used for e/a and PASP.Result1 The Left ventricular systolic function parameter of VSD and TOP measured by TVI and M-mode Echocardiography.(1) The Left ventricular systolic function of VSD measured by TVI and M-mode Echocardiography .(D Measured by TVI, the peak velocity of s of VSDS > VSDM and VSDL are : 4.89 ?.02 cm/s. 4.72 ?.0 cm/s and 4.83 + 1.01 cm/s, respectively, compared with the normal group peak velocity of s 4.69 ?0.83 cm/s, there is no significant difference .(P>0.05).(2) Measured by M-mode Echocardiography, the LVEF of VSDS ^SD^VSDL are : 0.69?.05, 0.7+0.05 and 0.64+0.01, respectively, compared with normal group LVEF 0.69 + 0.06, there is no significant difference((P>0.05).(2) The Left ventricular systolic function of TOP measured by TVI and M-mode Echocardiography.(D Measured by TVI, there is no significant difference between mild TOP peak velocity of s 3.77 + 1.27cm/s and normal matching group's 4.54?.92cm/s (P> 0.05). The moderate TOP peak velocity of s 3.45 + 1.23cm/s is lower than normal matching group's 4.24 + 0.73cm/s (P<0.05=. Also, the severe TOP peak velocity ofs 3.33?.53cm/s is lower than normal matching group's 4.83 ?.81cm/s (P<0.001)(2). Measured by M-mode echocardiograghy, ther... |
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