| The natural grazing Sunit Sheep with different ages were selected, the changes of intestinal mucosal structure and mucosal immunity-associated cells in small intestine of Sunit Sheep are investigated to clarify on the relationship of morphological structure of small intestinal mucosa with absorption ability and mucosal immunity, at the age of 0.5,1.5 and 3 age respectively, by the technique of histology, histochemistry.1. The length of villi shortened gradually with age bottoming at 1.5age,and turned to those lengthen thereafter. By 1.5 and 3 age, the villus lengths were noticeably lower than that at 0.5 age. No significant, however, were found between 0.5and 3 ages (P>0.05). The V/C valuefell promptly from the largest at 1.5 ages to the lowest at 3 ages. Then, it returned to increase till age 1.5, by which it is increased 5.78% compared with that of age 0.5 (P<0.05). There is a steady thickening in muscular layer, but not in intestinal wall over the whole experimental period, with the thickness at 1.5 age of age being 2.5times of that at 0.5 age. When the lacation was concern, the maximun of villus length was found in jejunum, which was replaced by duodenum after1.5 ages; the V/C value and the thickness of intestinal wall got maximal in jejunum and ileum respectively, except for that of the at 0.5 ages.2. The intraepithelial lymphocyte (IEL) sparsely spread in intestinal mucosa at ages 0.5 when the number was about 33.17±7.62 per1villi. Thereafter, the IEL increased gradually. The range of augumentation was more obvious in the groups of age1.5, which reached 229%. The density of IEL gradually reduced from age 1.5 to age 3 all the time.3. The number of goblet cell (GC) in mucosa declined steadily from age 0.5 to age 1.5 ,the highest number was at 3 ages (14.28±3.27 per1villi), but no significant were found from age 0.5 to age 1.5 (P > 0.05).4. The number of mast cells (MC) was sparse at 0.5 ages (17.87±4.28 per mm2), and increased to 35.79±8.60 per mm2 at 3 ages. |
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