The Pathology Research Of Swine Eperythrozoonosis

The Eperythrozoonosis is one Amphixenosis which causes by Eperythrozoon, which is onespecies of polymorphous microorganism that parasitizes the red cell surface, blood plasma andbone marrow. The clinical symptom of this sick is the depress of PRBC,degression of HC,leukocytosis,anaemiaand febricity.This experiment took nature infected Eperythrozoonosis young pigs for experimental animal.It took the blood smear method of inspection, the pathological anatomy, the histo-pathology andelectron microscope technology. In the foundation of blood smear dyeing observation, pathologicalanatomy and histo-pathology experiment, to use the scans electron microscope and thetransmission electron microscope, we take the ultrastructural pathology research for multiple point.The blood smear dyes observed result indicated the red blood cell presents the form of star-likerays and there were purple particles on the red cells surface. The pathological anatomy and thehisto-pathology observed result indicated that the sick pig each organization organ all have certaindamage, in particular liver, spleen, lymph node and lung quite serious. The ultrastructureobservation showed the fellowing results. The Eperythrozoon shew rhabditiform and the matureEperythrozoon carried on by the binary fission way reproduces. The Eperythrozoon had the modelnucleus biology structure, the Outside of The Eperythrozoon coat single-layer membranestructure, it had no obvious cell nucleus and the cell organ class structure in the metricalstructure, it's structure and nature similar was similar to RLB. The Eperythrozoon adhered to thered blood cell surface by the filament, it Causesd the red blood cell to distort, the breakage andcreated organism anemia. The Eperythrozoon destroy the single nucleus phagocyte system celland the cytoplasmic cell system of the organism and affected the organism's cellular immunity andthe humoral immunity function. It caused organism immunity level to be low.This experiment carry out systemic pathematology observation to the young pig that infectedEperythrozoonosis. We hope that we can take the dependable theoretical instruction for theresearch of pathogenic mechanism.