The Establishment Of Streptococcus Suis Type 2'S Infection In Mini-Swine Model And Study On Its Dynamic Distribution

The disease coused by Streptococcus suis type 2 had become one of the most important Amphixenosis worldwide focused, for it did not only cause the big economic loss in swine farming, but brought great threaten/threats to the public health and food security as well. The virulence factors of SS2 hadn't been deeply studied so far, and the dynamic distribution of SS2 in vivo hadn't been clear, which made it hard to have a further study in pathogenic mechanism. Consequently, it's greatly essential to set up an animal model in which clinical symptom and pathological change are similar with that of naturally infected animals, in order to have a further study on dynamic distribution, infection mechanism, virulence factors, and immune response of SS2 infection, which was of great significance to protect and control of this disease.(1)Setting up the mini-swine SS2 infected model. The SPF...