Epidemibiologic Investigation And Control Of The Porcine Circovirus Infection In Pigs In Zhangzhou

Porcine circovirus type 2 (PCV2) is the causative agent of porcine postweaningmultisystemic wasting syndrome (PMWS) that has become an emerging and importantdisease in swine. In the present study, PCR and ELISA were uesed to test samplescollected from Zhangzhou area for PCV2. The results showed that PCV2 infection hasbeen widely existing in Zhangzhou area. According to practical need, disinfectedhomogenate was used to protect from PCV2 infection in pigs, and the result wasexciting and encouraging. On the basis of this, useful methods were suggested to controlthe disease.1. Since August of 2004, epidemicbiologic investigation of 1.8 million pigs inZhangzhou was done. The results showed that PCV2 infection has been widelyexisting in swine populations in Zhangzhou, and multiplex infections has made itmore difficult to control. The morbidity of PCV2 infection was 5%-37% in swinepopulations, and mortality was up to 53%.2. ELISA was used to test 1635 serum samples from 86 swine populations inZhangzhou city.The results showed that PCV2 positive rate has reached 58.59%(958/1635). And the rate of sows was 60.60%, much higher than the ones ofpiglets(47.82%). 3. PCR technique was used to test 320 clinical samples from the August, 2004 toAugust, 2006. The results showed that positive rate of PCV2 infection was 53.75(172/320). At the same time, 280 samples from slaughter house was tested, andthe positive rate reached up to 9.28%(26/280). The results showed that PCV2infection has been widely existing in healthy swine populations.4. The organs, such as spleen, lungs, groin lymph nodes, mesentery lymph nodesand tonsils were pooled, diluted, ground by homogenization, and centrifuged. Thehomogenate was disinfected and injected in pigs. The results showed that pigs hadmore productive ability and less respiratory diseases than ones had no vaccine orhad only antimicrobile.5. According to the practical fact, many measures, such as vaccine innoculation,emphasized management, drugs and so on, had been taken to control the PCV2infection in pigs.