Effect Of Diet Supplemented With Ipriflavone On The Growth Performance And Endocrine Mechanisms Involved Of Rat And Broiler

The effect of ipriflavone on the growth performance in rats and broilers and related endocrine mechanisms were studied in this research which included three series:Series 1: Effect of ipriflavone on the growth performance in rats60 SD rats of 28-day-old were randomized into 3 groups: basal diet, basal diet plus 5mg/Kg ipriflavone, basal diet plus 5mg/Kg daidzein. The test last for 6 weeks. To male rats, results showed that ipriflavone could increase the body weight gain by 11.54%(P<0.05), decrease the ratio of feed intake and body gain by 11.06%, increase the ration of RNA and DNA by 14.98%(P<0.05), decrease the serum urea-N by 7.74%(P>0.05), increase serum GH by 3.12%(P>0.05), increase serum testosterone by 371.52%(P<0.01), decrease the activity of aromatase in testis by 57.64%(P<0.01), increase the activity of serum alkaline phosphatase by 9.51%(P>0.05), increase serum bone gla-protein by 15.88%(P<0.05), decrease serum calcium by 13.6%(P>0.05), decrease serum total cholesterol and triglycerides by 5.31%(P>0.05) and 20.56%(P<0.05), increase the activity of serum Lipoprotein Lipase by 19.08%(P>0.05).To female rats, results showed that ipriflavone could increase the body weight gain by 5.41%(P>0.05), decrease the ratio of feed intake and body gain by 11.38%, increase the ration of RNA and DNA by 15.58%(P<0.05), decrease the serum urea-N by 13.86%(P<0.01), increase serum GH by 23.51%(P<0.05), increase the activity of serum alkaline phosphatase by 22.76%(P<0.05), increase serum bone gla-protein by 52.29% (P<0.05), decrease serum calcium by 15.05%(P>0.05), decrease serum total cholesterol and triglycerides by 5.18%(P>0.05) and 21.24%(P<0.05), increase the activity of serum Lipoprotein Lipase by 14.74%(P>0.05).Series 2: Effect of ipriflavone on the growth performance in broilers63 Kuai-Da-Huang broilers of 30-day-old were randomized into 3 groups: basal diet, basal...