Analysis And Comparison Of Ventilator - Associated Pneumonia And Non - Ventilator - Associated Pneumonia Pathogens And Drug Resistance In Intensive Care Unit

Objective To investigate bacterial distribution and drug resistance between ventilator associated pneumonia and non- ventilator associated pneumonia in Intensive care unit(ICU), ICU physicians have a more reasonable basis for the use of antimicrobial agents.Method: The sputum specimens and lavage specimens that were submitted from ICU Jan2012 to Dec 2013 were retrospectively analyzed, the bacterial identification and drug susceptibility testing were performed by,and the date were statistically analyzed.Result : The top three species of pathogens isolated from ventilator associated pneumonias pecimens included Acinetobacter baumanii(26.68%),Pseudomonas aeruginosa(18.47%), Klebsiella Lei Bojun(14.08%),while The top three species of pathogens isolated from non ventilator associated pneumonias pecimens included Klebsiella pneumoniae(24.38%), Pseudomonas aeruginosa(21.55%), Escherichia coli(15.9%). The detectable rate of Klebsiella pneumoniae andthere was significant difference between the two groups(P<0.01),while Pseudomonas aeruginosa, Escherichia coli detection rate between the two groups had no significant difference.The drug resistance of pathogens isolated from ventilator associated pneumonias pecimens were common higher than non ventilator associated pneumonias pecimens.Conclusion: Composition and drug resistance of pathogens from ventilator-associated pneumonia and non ventilator-associated pneumonia are different,it is necessary for ICU physicians to grasp the distribution and drug resistance of the pathogen, which has a certain guiding significance for the use of antimicrobial drugs before results of drug sensitivity test.