Association Of Chronic Kidney Disease With Secondary Hyperparathyroidism And Analysis Of Physical

Purpose:Through the analysis of correlation analysis and physical types of related factors of chronic kidney disease patients with secondary hyperparathyroidism to understand CKD in patients with secondary hyperparathyroidism risk factors and physical type tendency。Material and method:Select the 189 patients from nephropathy Division of Liaoning University of Traditional Chinese Medicine in 2014 November ~ 2015 February for CKD, they are include 87 cases without elevated PTH, and 102 patients with elevated PTH.In accordance with the conditions of the two groups of patients were analyzed, including age, primary disease, sex, blood pressure(BP), serum creatinine(Scr), hemoglobin(Hb),carbon dioxide combining power(CO2CP),triglyceride(TG), cholesterol(TC),high density lipoprotein cholesterol(HDL-C), low density lipoprotein cholesterol(LDL-C),high-sensitivity C-reactive protein(CRP), serum albumin(Alb), urinary protein, calcium, phosphorus, etc.clinical data and biochemical parameters. Using Microsoft Excel software to establish the data table. Data with SPSS19.0 statistical software. The constitution is divided into nine types of constitution: flat and quality, Qi deficiency, Yang deficiency, yin deficiency, phlegm dampness, damp heat, Qi, blood stasis qualitative, special intrinsic quality.Results:1. General clinical data: 189 patients of chronic renal failure patients, primary disease in primary glomerular disease, a total of 64 cases(33.86%), followed by 46 cases of diabetic nephropathy(24.34%), 22 cases of hypertensivenephropathy(11.64%), 18 cases of chronic interstitial nephritis(9.52%), 11 cases of nephrotic syndrome syndrome(5.82%), chronic pyelonephritis in 7 cases(3.7%), polycystic kidney disease, gout, kidney for renal purpura in 4 cases(2.12%), 3 cases of lupus nephritis(1.59%), 2 cases of ANCA associated glomerulonephritis, IGA nephropathy(1.06%), hepatorenal syndrome, obstructive nephropathy for 1 cases(0.53%) 87 cases of 189 patients in the group with normal PTH(46%), 102 cases with elevated PTH(54%). Elevated PTH is more common in women than in men, The difference was statistically significant between the two groups(p<0.05). Hypertensive patients accounted for 76.32%, he difference was statistically significant between the two groups(p<0.05). And no statistical significance in age between the two groups(p>0.05). 2. Biochemical parameters between the two groups: Hb, Scr, CO2-CP, TG, CHOL, serum calcium, serum phosphorus index were statistically significant(p<0.05). Between the two groups LDL-C, HDL-C, plasma albumin, 24 hours urine protein, CRP, and other indicators showed no statistical significance(p>0.05). 3. Relationship: the rise of PTH positively correlated with Scr, serum phosphorus and other factors, negative correlation with Hb, CO2-CP, calcium. 4.Two yuan regression Logistic analysis Scr, serum calcium, serum phosphorus were independent risk factors of CKD with secondary hyperparathyroidism occurred(p<0.05). 5. 102 cases of chronic kidney disease with phase and physical existence of hyperparathyroidism patients, so the physical type of distribution: 42 cases of Yang deficiency(25%); blood stasis in 39 cases(23%); 35 cases of qi deficiency(21%); Yin deficiency in 24 cases(14%); 10 cases(accounting for phlegm dampness 6%); 9 cases of damp heat(5%); 3 cases of qi stagnation constitution(2%); 5 cases of flat and matter(3%); special intrinsic quality of 0 cases(0%). Among them the male accounted for 58 cases(57%), 44 cases were female(43%). Male patients with Yang deficiency in 22 cases(28%); 19 cases with blood stasis(24%); 16 cases of qi deficiency(20%); 10 cases(13%); Yindeficiency phlegm dampness in 8 cases(10%); 4 cases of flat and matter(5%); 1 cases of damp heat(accounted for 1%); Qi stagnation constitution in 0 cases(0%); special intrinsic quality of 0 cases(0%). 20 female patients with Qi deficiency(23%); 20 patients with Yang deficiency(23%); 20 cases with blood stasis(23%); Yin deficiency in 14 cases(16%); 8 cases of damp heat(9%); 3 cases of qi stagnation constitution(3%); 2 cases(accounting for phlegm dampness 2%); 1 cases of flat and matter(1%); special intrinsic quality of 0 cases(0%).Conclusion:1. CKD in patients with PTH increased in different degree, influenced by a variety of relevant factors, including gender, blood pressure, Hb, Scr, CO2-CP, TG, CHOL, serum calcium, phosphorus is the main factors related to secondary hyperparathyroidism. 2. Scr, serum calcium, serum phosphorus were independent risk factors of CKD with secondary hyperparathyroidism occurred. 3. CKD combined with secondary hyperparathyroidism TCM Constitution Types in both men and women were Yang deficiency, blood stasis and Qi deficiency is more common quality(more than 20%).