| Objectives:The factors about pediatric allergic purpura(PAP) are analyzed by sorting out and reviewing correlative documents, and also these factors’ influences on the syndrome pattern distribution are studied in this paper in order to improve the accuracy of diagnosing and treating the disease accordingly and enhance the treatment effect which can guide our everyday life as well.Methods:Aiming at children in the Pediatric Clinic and Pediatric Ward of Chengdu University of TCM, the process takes the way of field survey to collect150cases according with the inclusion criteria. The inclusion cases should fill the questionnaire for relevant elements and syndromes of HSPN truthfully. Then statistical analysis should be conducted on the collected materials by the spss18.0statistical software and Chi-square testing should be mainly used to make divergence analysis about all cases’ distribution, taking P<0.05as significant differences.Results:1. This disease was mainly seen in children under the age of14and there was a total of111cases within the age range of7-14years old, accounting for74%of total cases.2. The ratio of each factor in this disease was as follows:infection (37.4%), diet (24.0%), unknown (16.0%), drugs (13.3%), exercise induced fatigue (9.3%). Respiratory infection accounted for80.2%of the infection cases. Cases induced by eggs, milk, seafood, beef and mouton accounted for most cases in the diet category while physical exercise accounted for most cases in the exercise fatigue category (65.2%).3. There were a total of82recurrent cases (54.7%) and68primary cases (45.3%). Primary cases were mainly due to infection and unknown factors.4. Observation of recurrent cases:40patients were accompanied with three times or above recurrence of disease (48.8%) and the main causing factors were infection combined with diet (13.4%) and exercise induced fatigue (12.2%). Kidney functional impairment was worsened with increased recurrence rate.5. There were a total of57winter cases and41spring cases in this study, accounting for65.3%of all cases and22summer cases, accounting for14.7%.6. Of all the collected cases,69cases were accompanied with kidney impairment (46.0%). Kidney impairment could happen at any time during allergic purpura, but, it is mostly seen during the1st month or after the6th month of this illness.7. The syndrome ratio with an order from high to low was:Damp-heat in spleen and stomach (47.83%), syndrome of wind-heat injuring collaterals (26.69%), blood heat folly syndrome (10.54%), hyperactivity of fire due to yin deficiency (9.19%) and syndrome of qi failing to control blood (5.75%)。Conclusion:1. About pathogenesis of HSP, some children never show obvious inducement in the early stage, while among the founded inducements, infection stands as the major. In early HSP cases, chief pathogenesis lies in the unknown origin, while in the relapsing cases, infection and diet. Pathogenesis of HSP, to some extent, may be influenced by air pollution index, domestic animals, second-hand smoking, mildew phenomenon at home and recent decoration.2. The pathogenesis of HSP is principally at the age of7to14.3. The pathogenesis of HSP appears in the winter and spring in a maximum, while the autumn in a minimum.4. The renal damage caused by HSP may occur at any time, but primarily in the early stage (<1month) and later period (>6months)。5. In according to the investigation of150cases, the main syndromes and proportions are as followed:the spleen-stomach damp-heat syndrome accounts47.83%), the wind-heat injuring collaterals syndrome26.69%, the syndrome of bleeding due to blood-heat10.54%. the syndrome of hyperactivity of fire due to yin deficiency9.19%, and the syndrome of qi failing to control blood5.75%. Children with HSP in Chengdu are predominately infected with the spleen-stomach damp-heat syndrome.
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