Experimental Study On Treatment Of Dry Eye Mice By Acupuncture And Anti - Fumigation Of Ziyin Formula

Purpose：Experimental study on the treatment of dry eye with method oftraditional Chinese medicine onultrasonic atomization.Materials and methods:1material:Traditional Chinese medicine (born1.1, ophiopogon root,figwort,trichosanthes root, borneol), by the Affiliated Hospital of LiaoningUniversity of Traditional Chinese Medicine to provide raw materials1.2SPF Kunming mice were purchased from the animal experimental department,China Medical University, animal license No.: SCXK (Liaoning)2008-0005.1.3Etude eye drops, purchased from Santen, batch number:1TH3878.1.4rat pellet feed, animal feed as a standard rat feed, uniform providedby the animal center.1.5the402AI type ultrasonic atomizer (Xi’an Kangxin Medical Instrument Co.,Ltd)2method:2.1Decoction of Chinese medicine preparation,put in the container, and thentested on mice.2.2Establishment of animal model of dry eye2.3To observe the effect of mouse model of dry eye tear secretion;2.4Dry eye model by corneal fluorescence staining, to observe the effectoncorneal epithelium2.5Observation of ocular surface tissue pathological changes andconjunctivalgoblet cell number changes.Results:1.An ultrasonic atomization fumigating eyes can significantly increase thesecretion of tear; 2.The dry eye model mice corneal epithelium significantly repair;3.Ocular histopathological observations suggest that theinhibitorycornification of conjunctiva and corneal epithelial functionConclusion:1Chinese medicine atomization fumigating eyes can effectively increase the tearsecretion,(P <0.01). That can promote the secretion of tear.Atomization decreased corneal epithelial fluorescence staining, and murinemodel of dry eye group are statistically significant compared. It shows thatthe method of traditional Chinese medicine of ultrasonic atomization can improvethe nutritional status and promote cornealepithelial recoveryThrough the observation of ocular pathology, Chinese medicine ultrasonicatomization fumigating eyes though not completely the conjunctivaltissuereturned to normal, horny but he can fight the conjunctiva, and blankgroupand the control group were significantly different (P <0.05, P <0.01)Show thatChinese medicine atomization fumigating eyes can inhibitcornification ofconjunctiva.