Pathology Of Experimental FLS And Treatment Of "Qin Gan Tai" In Chickens

45-day-old chickens were fed on high-fat diet for studies on effects of Fatty Liver Syndrome(FLS) on organs, blood biochemical findings and blood viscosity by the methods of pathology, blood biochemistry and hemorrheology.Signs appeared in control group at 13 day. Pathologically, there was liver fatty degeneration in the affected chicken. The liver fat content, the liver index were markly increased(p<0.01).Hematologically, the serum aspartate aminotransferase(AST) the serum alanine aminotransferase(ALT) activities, the serm triacylglycerol(TG),cholesterol(CHOL) and low density lipoprotein cholesterol (LDL-C) contents were obviously increased(p<0.01 or p<0.05).The whole blood viscosity, plasm viscosity, whole blood reduced viscosity at high shear rate and whole blood reduced viscosity at low shear rate were also markedly increased(p<0.01). The erythrocyte sedimentation rate was evidently decreased(p<0.01). "Qin Gan Tai" not only markedly lowered the serum TG, CHOL, LDL-C contents, ALT, AST activies, but also remarkably lessened the steatosis degree.All of "Qin Gan Tai" remedical groups,the higest dose group (3g/chicken) was the best during the experiment. The aforementioned results demonstrated that FLS in the chicken could be successfully caused by high-fat diet. Chinese traditional medicine "Qin Gan Tai" (3g/chicken) had a key role in the treatment FLS.