| Objective:To compound Yuzhu prescription anti-fatigue as the main component of polysaccharide indicators,designed by orthogonal experimental methods of anti-fatigue compound Yuzhu of the water of traditional Chinese medicine,Yuzhu compound of anti-fatigue beverages and the preparation of effervescent tablets And to evaluate the anti-fatigue compound Yuzhu of the prescription anti-fatigue effects.Method:(1)by orthogonal experimental study of water and decocting time,the number of prescriptions extract decoction of polysaccharide and extraction of the impact of the sensitivity of factors to determine the prescription of the polysaccharide content;To clarify the targets of the inspection results to clarify and evaluate their taste.(2)Preparation of anti-fatigue compound Yuzhu effervescent tablets,and the quality of evaluation.(3)the use of weight-bearing mice swimming test and evaluation pilot to climb at anti-fatigue compound Yuzhu drink anti-fatigue effects.Results:(1)This experimental extraction of the best prescription for 10 times the volume of water,soak 1 hour,decocting three times,each time 60 min;concentrated liquid medicine to health:liquid(that is,condensed coefficients)1:6,Heated to 80℃, 5 percent of the typeⅢZTC1+1B adsorption clarification of components,still holding 30 min,then cool down to 60℃to join the A component 2.5 percent,still holding 30 min,a centrifuge that is clarified liquid;Solution to concentrate dilution factor 1:20 per 500 ml,adding aspartame 0.05 percent,0.05 percent citric acid,sorbic acid 1.2 percent.(2)the acid-base separate granulation method of effervescent tablets of stable quality,simple process and is conducive to industrial mass production.(3) anti-fatigue compound Yuzhu drink three different dose groups of mice swimming time and negative control group were significantly extended(P<0.01),but also in the high-dose group swimming longer than the best-fitness group.Anti-fatigue compound Yuzhu to drink three different dose groups of mice crawling at the time and negative control group were significantly extended(P<0.01),but also in the high-dose group to climb the better-than-time fitness group.The results showed,that anti-fatigue compound Yuzhu drink anti-fatigue effect is better than the market's best-fitness beverages.Conclusion:The compound Yuzhu of the anti-fatigue beverage preparation of viable products for the bright yellow,liquid clarity,quality and stability,taste sweet and sour, and has a good anti-fatigue effects.Preparation of the compound by the anti-fatigue Yuzhu effervescent tablets with the quality of Chinese Pharmacopoeia standards. |