Synthesis And Characterization Of MixedTriorganotin Compounds Containing Silicon

Most of trialkytin complexes have biological activity, and their activity will be changed with diffence of alkyl radical and ligand. In order to further study synthesis methods and reaction conditions of mixed Trialkyltin compound containing silicon, 9 new complexes containing silicon were synthesized. Their structures were characterized by IR,¹HNMR, ¹³CNMR.(1) (Me₃SiCH₂)Bu₂SnCl(2) (Me₃SiCH₂)Cy₂SnBr (3)(Me₃SiCH₂)₂BuSnCl(4) (Me₃SiCH₂)₂CySnCl(5) (Me₃SiCH₂)₂CySnOCOArAr=-C₆H₄-H, -C₆H₄-F-p, -C₆H₄-Cl-o, -C₆H₄-NO₂-p, -C₆H₄-NO₂-m.The experiment results show that, for mixed trialkytin compounds with different alkyl can be synthesized by different methods, It has longer synthesis routes and lower total yield using concentrated hydrochloric acid, but the purity of the target compounds is high and post-processing is simple; It has shorter synthesis routes and higher yield using the reaction of diorganotin dichlorides and Grignard reagents, but purity of the target compound is lower and it may contain a small amount of tetraorganotin. So we can sythesis mixed trialkytin compounds containing silicon according to different methods .In this paper, using a variety of different methods to synthesize mixed triorganotin containing silicon may enrich the study of organotin chemistry and find out the best way to synthetic organotin compounds has done some exploratory work.