Mechanism Of Reactive Oxygen Species In Synthesizing Lycopene For Blakesiea Trispora

Reactive oxygen species (ROS), including superoxide radicals(O₂^-), hydrogen peroxide (H₂O₂) and hydroxyl radicals (OH) are a group of activated molecules that continuously formed during normal aerobic metabolism. The condition known as oxidative stress results when the production of ROS exceeds the capacity of the cells to remove lipid peroxidation, lead further to disruption of normal metabolism, mutations, and ultimately cell death. To protect cells against ROS, all aerobic micro-organism instinctively respond to the stress using enzymatic and non-enzymatic defence systems, and thus show different biological phenomenon. It has been proven that the changes of activeties of antioxidative enzyme, including superoxide dismutase (SOD) and catalase (CAT), can directly reflect the level of cells to understand the causation of human disease caused by ROS and find effective means of protection and clearance.In this paper, a high yield strain produced lycopene andβ-carotene, Blakeslea trispora was studied, the oxdative response of micro-organisms to different forms of ROS stress including separated stress (H₂O₂) and different mode of stress (instantaneous and continual), were investiganted by using diverse generating source of ROS, which were characterized by synthesis of CAT, the most important enzymes in microbial in protection against oxidative stress and environmental stress were discussed.