Optimization Study On The Extraction Conduction Of The Chondroitin Sulfate

Chondroitin sulfate is the basis of connective tissue of the mammalian, it mostly distributes cartilage, nose, throat, ligament and myolemma, especialy fish cartilage. CS is mostly used to treat neuralgia, arthritis, tinnitus, along with accelerating canker cicatrisation and preventing hyperlipemia. With lucubrating physiological action and biochemical character of CS, the effect of curor and preventing vein harden is also found .There is preferable curative effect for the preventing of coronary heart disease and myocardial infarction.CS can protect nerve cell, mucosal cell,kindey cell. CS is also executed toiletry mixed with something to protect cutaneous beauty.Chicken breast is used as testing material to choose the best pick-up technnics of CS in the study. CS are extracted by using neutral salt extraction, alkali extraction, enzyme extraction, ultrasonic extraction and acetic acid extraction.Single. Alkali extraction makes serious pollution. The cost of single enzyme extraction is high. The method of dilute alkali-enzyme hydrolysis is used in the test. The key of the study is how to save materials, reduce environment pollution and improve the yield and quality of CS.As CS band with protein, alkali extraction is propitious to destoty covalent bond among CS and protein to release CS. The process of alkali hydrolysis is the key of extracting CS. The process of emzyme hydrolyze is the main technology of improving production purity. Protein is one of the most impotant extraneous compontents of CS. Through emzyme hydrolyze, protein of the long chain among liquor and CS is more destoried and becomes soluble small molecule , such as peptide, amino acid. As it is difficult to reach the standard by using one kind of emzyme , the study uses two kinds of emzyme hydrolysis. The result is as follows:(â… ):In the process of alkali hydrolysis some factors influence the effect of the production yield including ratio of cartilage quality and lye liquor, lye consistency, reaction temperature, PH, reaction time, have been investigated and screened out. The factors influencing the effect of the production yield have been investigated through...