Studies On Process, Quality Standard And Stability Of Limonene Soft Capsules

Limonene is volatile oil that is from the wet skin of Cirtus reticulata Blanco through cold squeeze refined. Its main component is limonene {C10H16, chemistry name is:1-Methyl-4-(1-Methyl vinyl), no less than 80%}.Limonene capsules have flabby oddi sphincter and the degradation guts pressure action, mainly used cholecystitis, cholangitis and guts calxulus. But taking amount is great, and with horary extension in storage, the content of it drops form of a drug to act as the limonene soft capsules, in order to lift stability and bioequivalent of its volatile oil and reduce a dosage.For limonene is volatile oil, it prepares the soft capsule with the pressing process. The component proportion tests of the soft capsule pocket fix the proportion of glycerol. In the stability research on the content, two kinds of evaluation indexes梖ingerprint and determination of it are selected to evaluate the sort and proportion of antioxidant. In contrast to determination, the fingerprint of limonene can evaluate the quality of the content more completely. During the evaluation process of the fingerprint diagram, the limonene standard fingerprint is established, that can be ensure the quality of limonene . After that, though pressing process, limonene soft capsules are manufactured . In the end, quality standard and stability of it are researched.In short, through studies on process, quality standard and stability of limonene soft capsules, it attained the aim that we anticipate.