| Bioactives of onion have extensive medical effect. The non-destructed extraction has significane application and theroetical meaning. The paper studied the process for extraction of onion oil in vacuum distillation suitable for manufacture.The study on the process inculded vacuum degree, soak condition, selection of variety, to optimize and determine the process for extraction of high yield and quality onion oil and apply in factorial manufacture. Following is the process:homogenizedroom temperaturevacuum distillatmgOnion bulbs?homogenatehomogenatestanding5-8KpaDistillation ~ extraction distil ating omoti cii.CH2C12The sensible shape and proporties and chemical analysis showed that the omen oil extracted from the process has a significantly superior quality to that from steamdistillation at atm, and close to that from SC-CO2. The test on pharmacodynamices showed that the oil has the notable medical effect of lowering choleslor and triglycerides in mice, similar to the effect of Etophylline clobrate, and superior to that of solvent-extraction oil. |