The Distribition Of Sequence Informational Parameters Of Different Kinds Of Sequences Along The Chromosomes Of Drosophila Melanogaster Genome

Because the complexity of eukaryote genomes in the arrangement and constitution of different kinds of genes and sequence segment, so the DNA sequences in Drosophila melanogaster chromosomes are divided into five kinds of sequences: complete DNA, intergenic, intron, coding and gene sequence respectively. Four information parameters are used to describe sequence characters. For different kinds of sequences, the distributions of the four information parameters along chromosomes are gotten and the characters of these distributions are analyzed. We also use linear and polynomial fit to analyze their distribution trends and differences among chromosomes and among different kinds of sequences (student t test). We focus the analysis on the distribution rule in pericentromeric region. Results show that the GC content of each kind of sequences is lower in pericentromeric regions than in other regions in autosomes eliminating 4 chromosome,, but it is opposite in X chromosome. In analysis of D₂ distributions of the five kinds of sequences along each...