| ObjectiveLingnan is located in the South China Sea of the motherland.It’s hot and humid.and easy to cause atrophy-flaccidity.The unique geographical environment is also rich in Lingnan herbs,which have a good effect on the treatment of this disease.Lingnan doctors in the past dynasties on the treatment of atrophy-flaccidity is far-sightedness.This study attempts to provide reference for the modern treatment of atrophy-flaccidity,through sorting out the treatment experience of Lingnan doctors in the past dynasties,and excavating the treatment of Lingnan herbs.MethodsThe research method uses literature research,theory review and data mining in combination.Literature research includes data search,identification and sorting.The collected first-hand data will be photographed and saved,sorted into Word documents,and compiled according to historical stages.The method of this study focuses on the original works of relevant ancient books.The modern treatment of atrophy-flaccidity is based on the collection of medical cases from journals and libraries.Theory review,according to the historical period of the review,use traditional interpretation,disease and syndrome analysis,tracing to the source,horizontal and vertical comparison etc.to classify and summary the Lingnan doctors’s recognization of the treatment of the academic source of atrophy-flaccidity to explore its academic connotation and clinical value.Data mining use modern information technology to analysis of clinical diagnosis and treatment of patients with atrophy-flaccidity,in order to mine the rule of medication,ResultsA total of 121 ancient books were consulted,among which 42 were Lingnan medical books related to atrophy-flaccidity.Before the Ming Dynasty,there were mainly Ge Hong’s Zhouhou Beiji Fang,Li Xun’s Haiyao Bencao,Shi Jihong’s Lingnan Weisheng Fang,Danliao Ji Yanfang,Sheng Duanming’s Chengzhai Yichao Miben and so on.The majority of medical works were written in the Qing Dynasty,mainly including Ye Cha Shan’s Cai Ai Bianyi,Liu Yuan’s Yixue Zuanyao,He Mengyao’s Yi Bian,Guo Yuanfeng’s Mai Ru,Deng Youfeng’s Xulao Li Zhuo,Huang Yan’s Yixue Jingyao,Pan Mingxiong’s Ye An Kuoyao,Chen Yaochen’s Nanyi Bianlun,Chen Zhenge’s Yigang Zhongshu etc.During the period of the Min Guo,there were Huang Enrong’s Huixi Yian Tangren Fa,Xiao Budan’s Lingnan Caiyao lu,Lu Jueyu’s Juelu Yian Xinjie Fu Yihua Lu Cun etc.The first part of the paper reviews ancient books and literatures on the treatment of atrophy-flaccidity by Lingnan doctors from the Jin and Tang Dynasties to the Min Guo,mainly from the aspects of the recognition of the disease name and location of atrophy-flaccidity,etiology and pathogenesis,treatment and medicine for the treatment of atrophy-flaccidity.The results are as follows:1.Name and location of disease:From Jin and Tang Dynasties to the Min Guo Period,doctors in Lingnan gradually recognized and deepened the atrophy-flaccidity.The name of atrophy-flaccidity appeared for the first time in the Song Dynasty,and the classification of atrophy-flaccidity appeared in the Qing Dynasty.From the Ming Dynasty Lingnan doctors began to identify similar diseases of atrophy-flaccidity,first atrophy-flaccidity and syncope.In the late Qing Dynasty,Zeng Chaoran took the lead in distinguishing atrophy-flaccidity from weak foot..In terms of disease location,considering the idea of Lingnan Weisheng Fang about fascia,Neijing about tendon,fascia and moyuan,Yigang Zhongshu about weijin,and the clinical manifestations of atrophy-flaccidity,we can presume fascia contact tendon into a net,full of body,nourishing by blood,and it has the function of leading body joint movement and protecting qi and blood..Qi deficiency and weak blood,can cause the disease of tendon and fascia,and then and atrophy-flaccidity.According to the different position of the injury,the atrophy-flaccidity presents a complex diversity.2.Eetiology and mechanism:from Jin and Tang Dynasties to Min Guo,the understanding of the etiology and mechanism of atrophy-flaccidity among Lingnan doctors was increasingly complicated.In the Jin,Tang,Song and Yuan Dynasties,the deficiency was the main factor.In Ming Dynasty,under the influence of famous doctors such as Li Dongyuan and Zhu Danxi,the main etiology and mechanism were weakness of spleen-stomach and dampness-heat soaking.With the increase of doctors introduced in the Qing Dynasty,the etiology and pathogenesis became more abundant.Among them,endogenous deficiency and impairment,deficiency of liver and kidney,weakness of spleen-stomach,leaf coke of lung and dampness-heat soaking are the most common.Overall,the endogenous deficiency was the main cause.3.Atrophy-flaccidity treatment:In Jin,Tang,Song and Yuan dynasties,tonifying was the main treatment.In Ming Dynasty,doctors attached great importance to the spleen and stomach,and clearing away the pathogen of dampness or heat.In Qing Dynasty,the treatment methods became increasingly abundant,especially the tonifying.There appeared many new treament such as clearing heat of lung,adjusting the mood etc.On the whole,most of them were treatments with tonifying,followed by clearing heat of lung,clearing heat and removing dampness,regulating spleen and stomach etc.Shi jihong put forward many ideas about tonifying.When tonifying the deficiency of spleen and kindey,doctors should pay attention to the compatibilty of medicines;When tonifying the essence of kindey,doctors should protect the stomach.So Lingnan doctors payed attention to warmth and Tongli,such as added Fennel to warm and move qi,etc.Shi jihong also pointed out the tonic didn’t last long.Consistented with this,Deng tietao and Liu xiaobin often took two or three alternatedly when keeping the core regimen unchanged.Trauma caused blood loss could tonify with shiquan yangrong decoction,and could use dabu weijin decoction to tonify the qi and blood.Among these,there had a poisonous medicine,nux vomica.It was often used with Liquorice Root in clinic now.Lingnan doctors also payed attention to regulating qi,such as spleen and stomach deficiency caused the abnormal rise and fall of qi,they used Buzhongyiqi decoction to treat it;When the cause is the heat of lung,treatment was more to nourish Yin to clear heat.Doctors also used Dwarf Lily turf Tuber,Coastal Glehnia Root,and Dendrobium etc.to nourish the Yin of the lung and stomach,with Mulberry Leaf,Bitter Apricot Seed,and Gypsum etc.to clear the heat of lung.When appeared emotional disorders,in addition to treat with drugs,doctors could also learn from Deng Youfeng with heart medicine to treat heart disease.He advocated to imitate Huineng Zunzhe,understanding their own heart,then atrophy-flaccidity could be cured.The method of clearing the pathogen of dampness and heat can be learned from Li Dongyuan.If the heat and humidity are accompanied by Yang deficiency,when clearing the heat and dryness,doctors used Radix Aconitae and Cinnamon to warm it..If it was serious,He Mengyao also treated it with Xiaowei pills.When deficiency of liver and kidney meeted with the pathogen of wind cold,doctors used Ephedra,Double-teeth Pubescent Angelica Root,Divaricate Saposhnikovia Root,or Herba Siegesbeckiae,mulberry leaves to get rid of the pathogen of wind cold,and then nourishing.4.The inheritance of the academic thoughts of the introduced doctors are mainly reflected in the selection of diseases and medicine taking into account the characteristics of Lingnan,such as Sheng Duanming’s copying treatment of weak foot from Sun Simiao.He Mengyao of the Qing Dynasty studied from Wang Kentang,but he hardly used the medicines of warming and removing dampness etc.when taking into account the climate of Lingnan.Another Inheriting characteristic is the creative application of theory,such as Deng Youfeng used Yu Jiayan’s atmospheric theory in the treatment of atrophy-flaccidity.5.In three herbal medicine works of Lingnan,only "shida gonglao" can treat the syndrome of atrophy-flaccidity.According to clinical characteristics of atrophy-flaccidity card,"strong waist and foot","strong bones and muscles" and so on can also be used in the treatment of atrophy-flaccidity.There have 31 medicines of this kind,among which Mai Muzi has been recorded in Kaibao Bencao.Pan Mingxiong used Obscured Homalomena Rhizome treat atrophy-flaccidity;Deng Tietao’s learn team often plus Lingnan herbals such as Radix Fici Hirtae,Radix millettiae Speciosae,or Obscured Homalomena Rhizome when treating atrophy-flaccidity.In addition,Shida Gonglao,Chili Head and Zou Ma Jian can be made into food therapy prescription to treat atrophy-flaccidity.The second part uses the combination of medical case analysis and data mining analysis to explore the academic experience and inheritance of modern Lingnan atrophy-flaccidity treatment.Medical case was mainly used to analyze the experience of treating atrophy-flaccidity of modern Lingnan famous old Chinese doctors.Through the inquiry,Chen Jinsheng,Chen Dianzhou,Deng Tietao,Yang Wenhuiand other 10 doctors in total had treatment records of atrophy-flaccidity.The characteristics of them could be summarized as:the name of the disease was in line with western medicine.Most atrophy-flaccidity had the deficiency syndrome,so the treatments were mainly tonification,especially warming spleen and kidney.If the deficiency caused blood stasis etc.they used radix curcumae longae,;Or Danpi,soil turtle worm,to remove;If the deficiency caused the internal wind,they used bombyx batryticatus,Buthus martensi karsch and scolopendra to expel the pathogenic wind.They began to pay attention to use southern medicine treat the disease,such as Radix Fici Hirtae etc.Another feature of the inheritance is the integration of many doctors’ ideas to treat atrophy-flaccidity,such as Deng Tietao integrating the idea of Li Dongyuan’s Buzhong Yiqi Decoction and Wang Qingren’s Buyang Huanwu Decoction with large dose of Milkvetch Root into his Qiangji Jianli drink when treatment atrophy-flaccidity.Data mining was used to analyze the characteristics of treatment of atrophy-flaccidity by Liu Xiaobin.The result showed that the commonly medicines had the functions of raising qi movement such as Milkvetch Root,Largetrifoliolious Bugbane Rhizome and so on,replenishing qi and invigorating spleen such as Largehead Atractylodes Rhizome,Common Yam Rhizome and so on,reinforcing kidney essence with Asiatic Cornelian Cherry Fruit and Prepared Rehmannia Root and so on.In terms of flavor and meridian tropism,warm and mild drugs were used most,followed by mild cold and mild warm drugs.The use of sweet drugs accounted for more than half,followed by acrid and bitter drugs.Drugs mostly enter the spleen meridian.These reflected the treatment of atrophy-flaccidity is mainly to replenish qi and invigorate spleen and kidney with warm,always caring for the spleen and stomach.And the results of community analysis showed that there were many overlapping areas in the four communities,which reflected the idea of treating different neuromuscular diseases with the same method.The core prescription for treatment of atrophy-flaccidity can be obtained by using complex network analysis,which is sorted according to the average dose size as follows:Milkvetch Root(50.54),Radix Fici Hirtae(50.18),Tangshen(25.84),Asiatic Cornelian Cherry Fruit(13.47),Largehead Atractylodes Rhizome(13.43),Chinese Thorowax Root(8.68),Largetrifoliolious Bugbane Rhizome(8.68),Chinese Angelica(8.65),Liquorice Root(5.06),Dried Tangerine Peel(5).Due to the chronic of the atrophy-flaccidity,adding Asiatic Cornelian Cherry Fruit to Qiangji jianli Drink is the perfection and development of Deng Tietao’s throught.The whole medication rule is very consistent with Liu Xiaobin’s clinical practice.ConclusionThis study through sorting the ancient literature on the treatment of Lingnan atrophy-flaccidity from the Jin and Tang Dynasties up to now,drawed the following conclusions:First,there were many insights in the cognition of atrophy-flaccidity in Lingnan doctors,such as Shi jihong about tonifying and Chen zhenge about weijin etc.Their viewpoint deserved further study.The treatment of atrophy-flaccidity by Lingnan doctors was manifested in three characteristics:tonifying,regulating the movement of qi,and Tongli Maidao.The combination of multiple zang organs when tonifying should take into account the nature of various zang organs and pay attention to the compatibility of medicines.Emotional diseases are the most harmful to the movement of qi.If more attention are paid to patients’ psychology during treatment,the therapeutic can be improved.Second,before the Minguo,Lingnan famous doctors were mostly foreigners,and the treatment of atrophy-flaccidity were mainly based on the idears of the introduced doctors.so there were few records of using Lingnan herbals to treatment this diseases in Lingnan ancient medical books.Herbs of Lingnan such as Obscured Homalomena Rhizome,Radix Fici Hirtae,Radix millettiae Speciosae and Herba siegesbeckiae have played a better role in the treatment of Lingnan atrophy-flaccidity.Therefore,modern Lingnan doctors can try to use more Lingnan herbs in the treatment or research of the atrophy-flaccidity.Thirdly,based on the discussion of tendon and fascia in Lingnan ancient medical books,it is believed that fascia connects tendon into a net,which are densely wrapped around the body and inside and outside the viscera.They have the function of barrier and in charge of the movement of limb and joint.so it is believed that they are the location of atrophy-flaccidity.According to the different position of the tendon and fascia injury,the syndrome of atrophy-flaccidity presents diversity.Qi deficiency and weak blood,the tendon and fascia impotent are the endogenous causes of atrophy-flaccidity.So make the body blood filling,the qi movement normally,and the maidao tongli are the main therapeutic rules of atrophy-flaccidity. 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