| he design, construction and operation of Manitoba TOF II, a reflecting time-of-flight mass spectrometer is described. In particular, the details of design and construction of the ion mirror are discussed. The principle of velocity focusing with a single-stage ion mirror and the effect of the acceleration region are described and discussed.;The principle and operation of the reflecting instrument as a tandem mass spectrometer is described; this involves correlated detection of neutral and ionized fragments. The efficiency, resolution, sensitivity, and mass determination of daughter ions by this method are described and discussed.;Methods of sample preparation are described. By using a nitrocellulose substrate, organic molecular ions as large as bovine insulin (MW 5733) were detected for the first time with low energy (keV) ion bombardment of a solid surface. Many daughter ion spectra resulting from metastable decay of parent ions have been studied. Secondary ions ((CsI);The performance of the reflecting instrument is described. Its detection limit is illustrated by observation of (M + H)... |
