| his dissertation describes the sequences attribute method developed to determine quantitative relationships between protein secondary structure and amino acid sequence's physical chemical and statistical properties. A sequence attribute is defined as a numerical characteristic calculated from the properties of a contiguous set of amino acids. Two types of sequence attributes are identified: chemical and statistical. Hydropathy and hydrophobic moment, averaged over a set of contiguous amino acids, are examples of chemical attributes. Chou-Fasman conformational parameters, averaged over a contiguous set of amino acids, e.g., ;The second part of this dissertation examines the highly unusual shape of the circular dichroism (CD) spectrum of the fd phage. The fd CD spectrum exhibits both the 208 nm parallel... |
