Precision sequence-specific cleavage of nucleic acids by minor-groove directed metal binding ligands linked through N-2 of deoxyguanosine

Posted on:1997-04-19

Degree:Ph.D

Type:Dissertation

University:Purdue University

Candidate:Gerry, Norman Phillip

Full Text:PDF

GTID:1461390014481377

Subject:Organic Chemistry

Abstract/Summary:

1,10-Phenanthroline was covalently linked from its 2-position to the N;In the presence of Fe(II), oxygen, and dithiothreitol (25...

Keywords/Search Tags:

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