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Silicon nanowires as intracellular devices

Posted on:2017-10-24Degree:Ph.DType:Dissertation
University:The University of ChicagoCandidate:Zimmerman, John FFull Text:PDF
GTID:1458390008973239Subject:Biochemistry
Abstract/Summary:
Semiconductor nanowire devices are an exciting class of materials for biomedical and electrophysiology applications, with current studies primarily delivering substrate bound devices through mechanical abrasion or electroporation. However, the ability to distribute these devices in a drug-like fashion is an important step in developing next-generation active therapeutic devices. In this work, we will discuss the interaction of label free Silicon nanowires (SiNWs) with cellular systems, showing that they can be internalized in multiple cell lines, and undergo an active 'burst-like' transport process. (Abstract shortened by ProQuest.).
Keywords/Search Tags:Devices
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