Az edzesmunka hatasa a szteroidhormon profiljara es egyeb anyagcsere mutatokra kuzdo&huml;sportokban (Hungarian text)

The purpose of our study was to analyze and compare the effect of acute, all out type physical exercise on the level of serum and urine anabolic-catabolic hormones and the cyclooxigenase system mediators in combat sports.; The concentration of anabolic hormones in the serum, such as testosterone, DHEA and androstendione have significantly changed. The concentration of the main catabolic hormone, cortisol increased in judo players, but not in the karate group. The results of our study supports, that elite judoists were in excellent physical condition. The hormonal response due to the catabolic/anabolic effects is balanced. The karate players demonstrated no significant increase in serum cortisol level, the intensity of the treadmill test primarily strengthened the anabolic effects. We experienced no changes in catabolic effects. The changes of serum DHEA concentration is worth to note. We suggest, that the changes in the level of DHEA and the hormonal adaptation are important demonstrators of the improved physical capacity. The change in concentration of adrenal glands originated DHEA is less known, compared to cortisol and testosterone on the effect of exercise. We found significant increase in both groups (judo, karate), which supports that DHEA has an important effect on the adaptation of physical exercise.; The urine steroid profile showed a decrease in the level of inactive metabolites, androsterone and etiocholanolone in elite competitors. Among the analyzed hormones, we measured increase, although not significant, only in the concentration of DHEA and 11-beta-OH androsterone. This increase was negligible, so the level of 11-beta-OH androsterone eventually remained stabile throughout the exercise test. We suggest, that the elevated serumconcentration of DHEA and the metabolism in the liver explains the higher concentration.; The changes on the level of cyclooxigenase enzyme mediators are inversely related to exercise intensity. The changes in TXB2 are related to exercise intensity. We found, that physical activity has an effect on the level of PGE2 and TXB2 in the airways. We conclude, that these mediators have an important effect on the adaptation of the airways. The examination of biologically active substance - PGE2 and TXB 2 - is a useful indicator of execise-induced airway adaptation.