| OBJECTIVE1.To guide clinical practice and improve the clinical effect by studying and inheriting the academic thoughts and enriching clinical experience of Professor Sun.2.To inherit and develop the diagnosis and treatment ideas and characteristics of drug use by summarizing the experience in diagnosis and treatment of Professor Sun.3.To evaluate the functions of Sun's Chest Pain Formula on treating coronary heart disease(CHD)by observing the clinical effect using Sun's Chest Pain Formula to treat coronary heart disease.METHOD1.We arranged and summarized academic thought connotation and clinical experience of Professor Sun through hackling his family tradition of learning,tradition of inheritance with teachers and the way of study.2.We arranged the understanding of disease,empirical formula and specialist medicine of Professor Sun,summarized his experience in diagnosis and treatment of nine kinds of disease,through learning and treating in clinic from Professor Sun.3.100 patients were selected with coronary heart disease with phlegm and blood stasis and heart qi deficiency type,who were in accordance with the inclusion criteria,were randomly divided into the treatment group of 50 cases,the control group of 50 cases.There were no significant differences between two groups on age,gender,course of disease,complication and total scores of TCM symptoms before treatment,and the two groups were comparable(P<0.05).Patients in the treatment group were given Sun's Chest Pain Formula,2 times a day for 4 consecutive weeks;the control group was treated with Isosorbide Mononitrate,Atorvastatin Calcium Capsules,Aspirin Enteric Tablets,Trimetazidine Hydrochloride Capsules,for 4 consecutive weeks.The effects were observed respectively,then scores variation of individual symptoms and general symptoms,total scores of syndromes and overall syndrome effects,as well as changes of ECG and recidivisms were compared between the two groups before and after treatment.Statistical analysis methods:SPSS 17.0 software package for statistical analysis,measurement data with ±standard deviation,before and after treatment of the groups were compared using paired sample t test,and the two groups were compared using independent samples t test;general count data using chi square test count data,rank count data using rank sum test.RESULTS1.Academic Thoughts of Professor SunProtecting vital and preventing evil,retaining vital and restraining evil,promoting vital and resisting evil is the clinical academic thoughts of Professor Sun.Regulating qi and blood,balancing rise and fall,steady in and out is the characteristic of his clinic speculative thinking.Professor Sun pays more attention to form,syndrome-type,pulse and qi,argues the eight guiding principles of deficiency,excess,cold,hot,life,death,improve and worsen,makes regulating qi and promoting blood circulation and restraining evil decoction,creates and uses triple drug group flexibly,which is balanceable,smooth and steady.2.Clinical Experience of Professor SunHypertension:In the opinion of Professor Sun,hypertension was related to the Liver,up to heart,down to kidney.The principles of treating should be calming the liver and suppress yang,nourishing liver and kidney,clearing heart fire and quiet spirit.Professor Sun treated with Sun's gastrodin and gambirPlant decoction,which made remarkable curative effect.Rheumatic heart disease:In the opinion of Professor Sun,we should explore the cause from vital and evil.Phlegm and blood stasis,phlegm accumulates with stagnant blood was the pathogenesis of the disease.The principles of treating should be enhancing heart qi and quieting the heart spirit as the fundamental,while eliminating phlegm,dissipating blood stasis and expelling wind-damp for the symptoms.Based on the treatment according to syndrome differentiation,Professor Sun treated with Shengmai decoction adding china-root,mother-of-pearl and so on,which made good effect.Insomnia:In the opinion of Professor Sun,there were three types syndromes of insomnia,which were type of pathogenic fire derived from stagnation of liver-qi,type of heart-kidney imbalance and type of insufficiency of heart and spleen.By the clinical differential treatment,we get remarkable effect.Autumn asthma:In the opinion of Professor Sun,the incidence was closely related with the solar terms which were the prominent feature.Dry evil attack by the lung,the loss of the lung was the main pathogenesis.The principles of treating was benefiting qi for activating blood circulation and dispel wind and diffuse the lung and relieving cough and asthma.Professor Sun treated with Zhonghe calm mind and relieving asthma decoction,which get better curative effect.Lung cancer:In the opinion of Professor Sun,Qi Yin deficiency was the foundation,Phlegm and blood stasis formed lung cancer.The principles of treating was promoting vital and reducing phlegm and resolving masses.Professor Sun divided the Lung cancer into types by the period of illness:type of obstruction of pulmonary qi,type of phlegm heat internal depression and type of combination of phlegm and heat.Professor Sun treated with clearing lung and control cancer decoction based on pattern types,which get satisfied results.Stomach disease:It was thought that stomach likes wetness and hates dry,and was smoothly by passing down by Professor Sun.In clinic,Professor Sun was carefully to protect the yin of stomach,and treated with Sun's strengthening spleen and stomach prescription which get better curative effect.Irregular menses:In the opinion of Professor Sun,menstruation was the fundamental for woman.Comprehensive qi and blood recuperating and qi-blood-body fluid movement should be paid attention.According to the age,Professor Sun treated with Siwu decoction,Xiaoyao pill and Guipi decoction to regular menstruation,which made good effect.Leucorrhea diseases:In the opinion of Professor Sun,the relax Ren channel and Dai channel can easily lead to gynecological disease.He usually identifies the cause of illness according to the colour and shape and properties.Besides the treatment of pathogen and the decoction,Professor Sun usually used drug washout by the condition of illness,which get better curative effect.Aphoristic cyst:According to his treatment experience,Professor Sun pointed that the location of the disease was in the liver,spleen,kidney,and the basic pathogenesis was deficiency of Qi and blood,Phlegm accumulates with stagnant blood.The principles of treating were promoting vital and resisting evil,and resolve toxin and dissipate binds.Professor Sun created benefiting qi for activating blood circulation and inhibit tumor decoction,which get better curative effect.Clinic characteristics of drug using by Professor Sun:The importance of using drug by Professor Sun is to understand the medicine mechanism,principle,prescription and drugs.When in medicinal formula,Professor Sun arranged triple drug group according to the medicinal roles frame,which understood principle and prescription.In clinic,Professor Sun was targeted in choosing drugs,which include specific prescriptions and medications,essential drug and messenger drug.Triple drug group and practical experience of Professor Sun:Triple drug group come from the medicinal roles frame based on Traditional Chinese Medicine(TCM)theory of the balance between and yang and the harmony among the heaven,earth and man,which was divided into three types according to the function resisting evil group,promoting vital group and supplementary group.In clinic,to achieve the balance of qi and blood,Professor Sun adopts meaning of classical prescription and step out the drugs classical prescription,and then created formula with Triple drug group according to the medicinal roles frame.3.Clinical Research on Sun's Chest Pain Formiula in Treating Coronary Heart Disease The improved aspects in ECG:The total effective rate of the treatment group was 83.67%.The total effective rate of the control group was 75.00%.There were no significant difference between two groups(P>0.05).The improved aspects in the individual symptom scores:group that given Western medicine can relieve the symptoms of chest pain and tightness,and shortness of breath(P<0.05),while the same as the group that given Sun' s Chest Pain Formula.The effects of the treatment group was better than the control group improving the symptoms of breath shortness(P<0.05).The improved aspects on overall symptoms scores:after the treatment,the overall symptoms were significantly improved in both groups(P<0.01),and the improvement in the treatment group was better than that in the control group(P<0.01).The total effective rate of the treatment group was 89.79%,which was better than the control group with the rate of 70.83%(P<0.05).CONCLUSION1.Protecting vital and preventing evil,retaining vital and restraining evil,promoting vital and resisting evil is the clinical academic thoughts.Regulating qi and blood,balancing rise and fall;steady in and out is the characteristic of his clinic speculative thinking.2.Professor Sun has abundant experience and his unique views to etiology and pathogenesis of disease.He creates and uses triple drug group flexibly,which is balanceable,smooth and steady.3.There are significant effect of Sun's Chest Pain Formula in relieving the main symptoms,such as chest pain and tightness,and shortness of breath,on treating coronary heart disease with phlegm and blood stasis and heart qi deficiency type,which can improve prognosis,delay the development of angina pectoris.So,Sun's Chest Pain Formula is an effective prescription in treating coronary heart disease with phlegm and blood stasis and heart qi deficiency type,which is worth being popularized,applicated and researched. |
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