| Background:Old the clinical experience of TCM experts, academic expertise and academic thought is the masters of Chinese medicine through years of practice and gradually accumulate, repeated verification and inspection of useful the crystallization of the wisdom of traditional Chinese medicine. It represents the highest form of Chinese medicine practice, is the study of traditional Chinese medicine to become have a level of efficient way of TCM doctor, so inheritance, sorting experience of traditional Chinese medicine has important practical significance. Hu Chunshen professor more than 40 years, capable of huangdi neijing, skilled in syndrome differentiation, especially in internal medicine of traditional Chinese medicine, especially academic theory of cardiovascular and cerebrovascular diseases has formed its own unique treatment and modulation of ideas, academic thoughts and clinical experience of professor Hu Chunshen sorting, study is very valuable.Research purposes:Chronic heart failure is a world problem, traditional Chinese medicine can effectively improve the symptoms of patients with heart failure and cardiac function, delay the heart function damage. Of this study was to comprehensively summarize and organize Hu Chunshen professor’s academic thoughts and clinical experience, and based on the experience of developing the epidemiology of ideas, with professor Hu Chunshen advocated by the "glove pathogenesis theory" as the core, through the scientific research of TCM clinical treatment of chronic heart failure disease, to explore new ideas and new ways to treat the disease of Chinese medicine.Research methods:1. The system study four big and sages, classic, read classics and works of various genres, focus on learning, traced back, to fully understand the professor Hu Chunshen academic thought theory origin.2. Adopt the method of TCM doctor DaiTu, including visits to division and wards, oral face-to-face records, independent clinical practice, sum up experience, etc., induction, analysis, sorting extracting its academic thoughts and clinical experience.3. To the teacher’s academic thoughts in the form of clinical study to study, to further understand the connotation of the theory.4. The design method using randomized controlled research on teacher excels to treat the disease of chronic heart failure for scientific research, observation, statistics, analysis, scientific conclusions. The stilbene save operation method to treat chronic heart failure disease:adopt the method of randomized controlled research Gui,80 patients included in the standard of chronic heart failure patients were divided into treatment group and control group 40 cases, each all cases according to the illness needs to rest and (or) oxygen, appropriate limit salt intake, infection control. Control group according to the modern medicine for the treatment of chronic heart failure disease guidelines to give the most appropriate treatment:giving injunctions Sammy 20 mg, I times per day, monitoring of electrolyte, with the necessity of adding potassium; Choose bei that captopril tablets 10mg ACEI drugs,1 times a day; Digoxin 0.125 mg once daily, beta blockers choose metoprolol, in stable condition after heart failure, and start from small dose of 6.25 mg,1 times a day, after gradually increasing doses, right amount to maintain. According to the condition of heart failure need to take into consideration the adjustment of clinical treatment. Observation group in the control group of the same western medicine treatment based on syndrome types according to its add and subtract application of traditional Chinese medicine syndrome differentiation stilbene save heart soup oral therapy. A daily dose, three times in early to middle temperature,100 ml each time, half an hour before meals. Group therapy for 4 weeks.Stilbene art save heart soup:astragalus, atractylodes, radix angelicae sinensis, radix paeoniae rubra, safflower, peach kernel, rhizoma ligustici wallichii, earthworm, twotooth achyranthes root, salvia miltiorrhiza, poria cocos, cassia twig, licorice, etc, with good temperature Yang, the effect of invigorate the circulation of the water.Respectively before and after treatment in patients with symptoms of TCM (palpitations, abdominal distension, shortness of breath, fatigue, purple purple, edema, chest tightness) and signs (respiration, pulse and blood pressure, heart rate, weight, urine volume and oral hair sweet, jugular vein throb, lung’s pulse condition, etc.), the degree of edema, tongue, recorded before and after treatment in patients with brain natriuretic peptide (BNP) and cardiac color doppler echocardiography monitoring indicators, including monitoring of patients before and after treatment the SV (stroke), CI (cardiac index), CO (cardiac output), EF (ejection fraction), E (maximum) early diastolic ventricular filling speed, A maximum (late diastolic ventricular filling), E/A peak velocity peak velocity (E/A). The data for statistical analysis.The results of the study:Hu Chunshen professor wen has deep, is good at self-study, well-read, read classics, favouring the neijing, treatise on febrile disease and synopsis "and other classic works, learning qigong and martial arts, tuina massage the Chinese traditional culture, enrich the sages through the ages, the test in the various branches of clinical practice, and practise persistence of their own teaching practice and popularization, to preserve one’s health and medical diseases combined, profound comprehension and formed its own unique academic point of view, the epidemiology, its theory origin as follows:1 the huangdi neijing, reveals the guiding ideology of TCM prevention cure-", "a balance of Yin and Yang is the Outlines of the epidemiology; 2 according to "pivot" gas "the" medium suffer indignities juice, change and red "and" heart blood "in neijing, and" the theory of spleen and stomach, "" internal injuries taste, born all ills by" say, attaches great importance to the soil to fill in, at the same time focus on kidney thrift, manifests the benefit first, the thought of the day after tomorrow; Three famous doctor in qing dynasty Ye Tianshi proposed "in the early disease, long illness into collaterals to the main gas, complex main blood", "early as in the air, the long blood wound into the complex", professor Hu Chunshen clinical recommendations of chronic heart failure should be yiqi promoting blood circulation to remove blood stasis; 4 d homologous, borrow the Taoist thought and martial in tai chi chuan the sentence:"before and after the instinct, is about the skill, up and down is the mystery", Mr Hu notice before and after, left and right, up and down six corresponding relationship of harmonic, called "sixth and thought", used to guide clinical drug use.Hu Chunshen academic thought of professor roughly summarized as the following:1 in huangdi neijing, treatise on febrile disease, the golden chamber "and other classic works of traditional Chinese medicine clinical, form the epidemiological point of view; 2 using the philosophy of traditional Chinese medicine, pay attention to flat regulating Yin and Yang; 3 diagnosis emphasize four diagnostic parameter, observe and pathogenesis, and evidence-based medicine; 4 qi deficiency and blood stasis is the basic pathogenesis of chronic heart failure., used to "glove pathogenesis of deficiency qi promoting blood circulation to remove blood stasis and water treatment of qi deficiency blood stasis type of heart failure; 5 slow disease attaches great importance to the spleen and kidney; 6 advocate foster healing principles, advocating the concept of "cure not ill", advocates support the vital qi, dispel evil treatment principle, advocate preventive treatment of disease, diet and traditional massage health care and non-drug treatments such as exercise.Hu Chunshen professor standard heart failure patients overall pathogenesis for the virtual to real, qi, Yang deficiency loss for the foundation of pathogenesis, blood stasis and wet as the standard, the water and blood stasis mutual heart knot, after consumption of Yang is an important factor in its stubborn painless. For clinical syndrome differentiation of heart failure patients, from qi deficiency, Yang deficiency, blood stasis and water to drink, qi deficiency syndrome differentiation of heart failure disease should be based on, always with Yin and Yang, and blood stasis, haemorrheological nature, water wet, clinical when distinguish weight is light, use WenYangYi of qi, blood and water. Look back to Yang and blood and the relationship between water, according to Yang deficiency, blood stasis and level, the degree of water wet the priorities and the priorities of drug use. Mr Hu to "glove pathogenesis", good temperature Yang, qi and the academic thoughts of water needs to be further mining, refining and summarized.Hu Chunshen professor pay more attention to curing the disease, professor Hu Chunshen deep study huangdi neijing, credentials, huangdi nei jing, ask four gas god theory "in the" saint don’t cure disease cure, which have not been ill, don’t cure has not disorderly cure "and" of disease has become and medicine, is then conquer, Pi Jude thirsty and wear well, bucket and cast cone, not also late ", emphasize the importance of keeping in good health and the disease, to combine theory with practice, editor in chief of huangdi nei jing 50, rounding, the elderly practical zhang, the elderly practical tuning epidemiology, participated in the Chinese medical encyclopedia "and other works, and pay attention to the medical homologous, encourage use to cure patents, published" discuss about<> Canon who gas and qigong iron-cloth, thesis writing, such as "the Chinese qigong to learn actively practise kungfu mission.Professor Hu Chunshen drug characteristics analysis for:1 the centralizer and exorcism, spleen and kidney to; 2 are using the drugs, pay attention to establish the circle loop body, clinical often in amomum villosum, combination, dried tangerine or orange peel, bergamot and other products for facilitating amuse oneself; 3 attaches great importance to the relationship between qi and blood. Hu old think chronic disease disease vital qi deficiency is the key, debility blood feud, clinical should pay attention to the vital qi, such as astragalus membranaceus and angelica, qi and blood circulation is the more disease easily; 4 chronic diseases emphasizes the phlegm and remove blood stasis therapy. Clinical research results show that:1, combining Chinese and western medicine treatment of chronic heart failure, heart failure in patients with total value aspects:the observation group compared with control group, there are significant differences between at 99% confidence level, that save heart soup treatment effect of heart failure has significant advantages.2, in TCM symptoms curative effect:there are significant differences between observation group and control group (P< 0.05).On the improvement of individual symptoms curative effect of traditional Chinese medicine, in the heart palpitations, chest tightness, shortness of breath, swelling, fatigue, violet purple, abdominal distension, loose stools, etc., observation group than the control group had significant difference, that save heart soup have obvious advantages in improving clinical symptoms in patients with heart failure.3, in the aspect of improving cardiac function:two groups of patients after treatment than before treatment had significant difference (P< 0.01), also have obvious difference is compared between observation group and control group (P < 0.01), suggesting save heart soup have the effect that improves cardiac function in patients with heart failure.4, two groups of patients before and after the treatment of heart rate, blood pressure, product of two comparison:comparison in the group had significant difference (P< 0.05), but the contrast between group by t test, no statistical significance (P> 0.05). This experimental study may be due to time is shorter, the number of cases and other factors caused by less, if eliminate the effects of above factors is expected to get the ideal expected effect.5, observation of the index of blood brain natriuretic peptide, BNP level difference before and after treatment in both groups was statistically significant (P> 0.05), comparable; Comparison between the two group patients have significant difference (P<0.01). Stilbene art save heart decoction on chronic heart failure (sun be the spirit virtual deficiency, blood stasis water stop) patients have the effect that improve the index of brain natriuretic peptide levels.6, observation of the heart colour to exceed indicators:observation group before and after treatment of SV, CI, CO, E, E/A, EF has significant difference, the control group the SV, CI, CO, EF has significant differences, peak, A, E and E/A there was no significant difference. Comparison between groups, SV, CI and CO, EF, E/A, E peak has significant difference (P< 0.05). That save heart soup treatment of heart failure in increase myocardial contraction force, has the obvious superiority to increase cardiac output.7, in the aspects of security:the control group 2 patients appeared dizziness, headache and cough symptoms, alleviate by oneself not special treatment, more cases have no obvious adverse reactions.Before and after the treatment of chronic heart failure the total curative effect comparison: observation group total effective rate was 88.8% higher than the control group 68.6%, after Ridit analysis statistically significant difference (P< 0.05); Observation group significant efficiency is higher than the control group (P< 0.05).Conclusion:1 this study academic thoughts and clinical experience of professor Hu Chunshen the systemic summary and finishing, professor Hu Chunshen ideas and methods of diagnosis and treatment of cardiovascular and cerebrovascular diseases, clinical practical, effective, is a very precious experience of traditional Chinese medicine.2 the clinical scientific research shows that guided by the glove pathogenesis, on the premise of conventional treatment combined with western medicine "stilbene save heart soup" dialectical treatment of sun be the spirit virtual, blood stasis water stop heart disease has significant curative effect, can significantly reduce related clinical symptoms in patients with CHF, improve the prognosis of CHF patients and quality of life; Reduce the application of western medicine, reduce the side effects of western medicine, stilbene art save heart soup treatment of patients with chronic heart failure mechanism may be related to regulation of neuroendocrine mechanisms, against myocardial remodeling factors, such as further studies are needed to confirm. |
