| Research background:Mr. Li yuxian is a chief TCM physician doctor, who is the fifth national famous TCM director and guidance teacher. Teacher Li Yuxian has obtained rich clinical experience In the treatment of internal medicine, such as difficulty miscellaneous disease more than forty years. Especially good at spleen and stomach disease, lung disease, heart disease, liver disease, renal system diseases such as multidisciplinary disease diagnosis and treatment. Teacher Li is very rich academic and clinical experience in inspection, his unique academic ideas and clinical diagnosis and treatment experience requires students to arrange and finish digging, with the help of technical means to reveal the mechanism of modern medicine.In order to the name old doctor of traditional Chinese medicine academic thoughts and clinical experience better inheritance and carry forward.Research purpose:1. Through the theoretical study and follow the teacher practice, trace and organizing teacher Li's academic thought form origin, Summary and refining teacher Li treatment of internal system disease's academic thoughts and clinical experience. Special focus on finishing teacher Li's some new ideas about the theory of spleen and stomach and internal Zhuanbing characteristic of diagnosis and treatment experience, a more comprehensive inheritance teacher Li's medical disease diagnosis and treatment experience and academic thought essence.2. In order to fully study and inherit Li Yuxian teacher treatment of the digestive system of knotty chronic atrophic gastritis (the CAG) clinical experience, choose teacher Li most used in the clinical treatment of the CAG, and a very effective prescription " He stomach soup ", through the statistical analysis of many factors, science evaluation " He stomach soup" clinical curative effect for the treatment of the CAG. To further reveal " He stomach soup" mechanism in the treatment of the CAG.Research contents and methods:1.Theoretical research?Used the sorting analysis induction method and interview method, inductive learning teacher Li had in-depth study the essence of TCM classics and the past dynasties doctor works and basis, the evolution of trace teacher Li academic thoughts and the formation of the source, summarize and tease out Li Yuxian teacher's academic thoughts origin.? By adopting summarized and refining method and interview method, to the teacher learning, teacher Li's lectures, works and the interview communication, etc,for organize and mining, extracting teacher Li make a diagnosis and give treatment medical disease diagnosis and train of thought and theory system, summary form teacher Li medical academic thoughts.2. Clinical researchUsing randomized controlled design method, carried out "He stomach soup" clinical efficacy research for the treatment to the cold and hot of mixed type of the CAG, The 100 cases accord with the cold and hot of mixed type of the CAG belongs to the mixed weiwantong patients randomly divided into two groups. Treatment group of 50 cases were treated by "He stomach soup" avoid decoction oral treatment, The control group of 50 patients with the weifuchun slice of oral treatment, Two groups of patients with treatment for 12 weeks, application of integral before and after treatment (clinical symptom integral, gastroscope, histologic examination) and laboratory evaluation index (pepsinogen I and II, G17, etc)for statistical analysis, analysis and evaluation "and stomach soup" clinical curative effect,further explore "He stomach soup" mechanism for the treatment of the CAG.Research Results:1. Li Yuxian's academic thoughts originThe academic thought's formation of teacher Li is dependent on the teacher attunements, The classics of TCM and past dynasties doctor works. Among them, the academic thought form one of the most influential Chinese medicine there are three famous artists; Neijing academic theoretical systemTo his clinical thinking in the formation of the framework is based; The theory of typhoid miscellaneous disease theoretical system of six-channel differentiation and treatment of internal injuries of miscellaneous disease Zhuanbing designed clinical systemis are the clinical practice guidelines for him; Past dynasties literature thought essence enriched the connotation of his academic thought. Rough long-term clinical practice, eventually formed its unique internal miscellaneous diseases diagnosis and treatment thought system.2. Li Yuxian chief physician of internal summary of academic thoughts and clinical experienceIn view of the medical diagnosis and treatment of miscellaneous diseases, teacher Li pay special attention to the centralizer function of spleen and stomach in the evolutionand outcome of the disease. Special emphasis on the study of the theory of the "spleen and stomach theory", etc. For clinical diagnosis and treatment chronic and difficult miscellaneous diseases have a very good guide.Teacher Li division of each medical system disease has a more in-depth study, think of internal disease classification system, summarize the onset of their respective characteristics, disease evolution law, diagnosis and treatment, such as characteristic and key for disease identification and diagnosis of drug use in clinical practice, etc all have very good guidance.?To treat spleen, stomach and bowel diseases, Mr. Li believed that separate treatment or combination therapy need to combinate of diagnosis and treatment thoughts.?To treat liver and gallbladder diseases, Mr. Li claims think about the liver and gallbladder self-diseases, meridian disease, liver disease and other diseases of each other and become complex diseases, emotional disease, in these four categories to classify.?To treat lung diseases, Mr. Li claims think about Xinliangfuxinwen for heat disease of Waihanneire, use Jinshuixiangsheng for lung inside disease.?To treat diseases of the kidney system, Mr. Li classify kidney disease who according to individual disease have there different etiology and pathogenesis.?To treat diseases of the heart system, teacher Li pay attention to "The heart's Tongyintongyong"Teacher Li make a diagnosis and give treatment of internal system disease focus on the balance of Yin and Yang between Zang-fu, change of pathogenesis, spleen and stomach nourishing effect to body. Mr. Li classify disease as different categreology, and separate treatment, who believed that each disease from discrimination and pathogenesis treatment, choose the main prescription, dialectical medicine to choice, Mr Li created all kinds of treatment and prescriptions, wchich can unilaterally using single method, or can be used as more method, proved recipe combination of, or add and subtract using. He is good at medical difficulty miscellaneous disease, for xiongbi, heart palpitations, heart failure, lung cancer, renal cancer, liver cancer, weiwantong treatment, to cure all these diseases have his unique insights.(1) The xiongbi always shows xushijiaza. It is due to lack of yangqi in heart, and a variety of pathogenic factor, phlegm and blood stasis block heart come on disease. Mr. Li to treat these disease take huatankuanxiong and yiqitongmai methods in clinic.(2) The occurrence of heart palpitations is close to Yangqi disorder, it is difficult to cure xinyangbuzu and xuexuxueyu disease. Mr. Li to treat these disease take wenyangtongmai and buxueninxin methods in clinic.(3) According to the region of vertigo local disease characteristics, due to yinxuyangkang and tanyuhujie see more quite. Mr. Li to treat these disease take zishengpinggan, huantantongmai and jianpixiezhuo methods in clinic.(4) Heart failure causes complicated, based on heart and lung two virtual, phlegm, blood stasis, shuiying and other pathological factors, Mr. Li to treat these disease take yiqiqiangxin, huatantongmai and wenyanglishui methods in clinic.(5) To treat stroke attaches great importance to benqizibing and xieqi. Mr. Li advocated in installment for treatment, using yiqitongmai and huatankaiqiao methods to treat stroke can't talk.(6) To treat Lung disease of cough too long, Mr. Li treat these disease combinate lung and kidney. Mr. Li always take jinshuixiangsheng and huatanzhike methods in clinic.(7) To treat lung cancer, from the jiubingyinsun causing feishengliangxu and duxieneiyun differentiation.Mr. Li to treat these disease take jinshuixiangsheng and jieduxiaozheng methods in clinic.(8) To treat nephritis edema claims stage treatmen. The three organs lung, spleen, kidney together deficiency cause of shuizuqizhi differentiation. Mr. Li to treat these disease take jianpiliqi and wenshenlishui methods in clinic.(9) To treat renal cancer, from the spleen and kidney deficiency, shizudunin differentiation. Mr. Li to treat these disease take jianpiyishen and jieduxiezhuoxiaozheng methods in clinic.(10) To treat liver cancer, Mr. Li dignosise ganyupixu and shizuduning differentiation.Mr. Li to treat these disease take shuganjianpi and jieduxiaozheng methods in clinic.(11) To treat the CAG, Mr. Li dignosise the cold and hot of mixed typ, Mr. Li to treat these disease take xinkaigujiang and jiedushengji methods and so on methods in clinic.3. The student to mentor multidisciplinary clinical experience of diagnosis and treatment of miscellaneous diseases inheritance and innovationStudents through the mining Li Yuxian mentor clinical experience,in the process of refining tutor academic thoughts, benefit a lot, learning and using are improved, and make its TCM theory level is improved obviously, clinical practice ability has improved significantly. In the clinical application of bold flexible for diagnosis and treatment of the instructor, and can be innovative. Making her in multiple disciplines miscellaneous diseases diagnosis and treatment such as some respiratory system diseases, etc. Preliminary formed her own relatively complete diagnosis and treatment of innovative thinking, and has obtained the good clinical curative effect.4. Clinical research:"He stomach soup" application in the treatment of the cold and hot of mixed type of the CAG clinical studies, through statistical analysis, the treatment group in improving clinical symptoms curative effect is superior to control group; Gastroscope integral evaluation grade, the efficacy treatment group is better than that of the control group; According to the pathological histology of curative effect evaluation:univariate statistical analysis, the treatment group on the CAG gastric mucosal inflammatory change, atrophy, for curative effect is slightly better than the control group, to improve the curative effect of gastric mucosa was intestinal metaplasia to assess differences between the two groups have no statistical significance. Serological indexes evaluation, pepsinogen I curative effect of treatment group was obviously better than the control group,while the two groups of pepsinogen ?/? and gastric secrete element-17 comparison, curative effect is no statistical difference. By the laboratory results analysis showed that patients with histologic improvement and pepsinogen I, pepsinogen?/? , gastric secrete element-17 growth was positively correlated. The overall curative effect evaluation:the treatment group curative effect is slightly better than the control group.Research conclusion:1. Li Yuxian chief physician at the core of the academic thought is "The thinking through"of "treating disease in this" for diagnosis and treatment system, ?The balance of Yin and Yang for this view; ?The pathogenesis of this scale dynamic view;?The digest for this view of spleen and stomach. Attaches great importance to the spleen and stomach in difficulty miscellaneous disease evolution and outcome of nourishing effect.2. The diagnosis and treatment of internal diseases each system to system classification and Zhuanbing partition as the main line, each disease from discrimination and pathogenesis treatment,choose the main prescription,dialectical medicine add and subtract of the theory of medicine is his clinical experience.3. Mr Li think, the region more the CAG patients with the cold and hot of mixed type, Mr. Li clinical to use of xinkaikujiang and jiedushengji methods and so on methods to treat. Get very good clinical curative effect, the academic view confirmed by the clinical research results. |
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