| ObjectiveIn order to discuss its effectiveness, this topic takes randomized controlled study research method with the help of the clinical observation on Depression Three-Needle and Dingshen-Needle for Climacteric Insomnia. The Depression Three-Needle and Dingshen-Needle is taken as the treatment group and taking medicine is taken as the control group.MethodLiterature of the last decade is collected and studied. Aiming at the evolution of the understanding and treatment for the etiology and pathology of this disease, the recent development of the effect on Chinese medicine for Climacteric Insomnia is summarized.On clinical research aspect,90 Climacteric Insomnia patients who meet the requirements are divided into the treatment group (adopt Depression Three-Needle and Dingshen-Needle) and the control group (taking Estazolam lmg qn.) with a scale of 1:1. There are 45 patients in each group. Two groups are put in the same environment and treated respectively. In the treatment group, being treated three times a week,4 weeks for a course of treatment, the results are evaluated after 1 courses of treatment. The two groups before and after 1 courses of treatment were estimated and evaluated according to the Pittsburgh sleep quality rating scale (PSQI), Hamilton depression rating table (HAMD) and the unified sleep efficiency value evaluation, and hereby, to estimate the clinical curative effect of the treatment, and to compare and analyze the results.ResultsThe age, course of disease, the sleep rate of the two groups have shown no significant statistical difference upon inspection and their base lines are identical, so they are comparable (P>0.05).1. Total effective rateAccording to the unified sleep efficiency value, in the treatment group, 17 are cured,18 have made significant progress,7 have made progress,3 show no change after the treatment. The total effective rate is 93.33%. In the control group,10 are cured,16 have made significant progress,13 have made progress,6 shows no change after the treatment. The total effective rate is 86.67%. According to the rank-sum test, total effective rate of the two groups was statistically significant (P<0.05), suggesting that the efficacy of the treatment group is superior to the control group.2. PSQI scale①PSQI score in different dimensionsOn Sleep quality of PSQI aspect, the Sleep quality of PSQI scores for both groups before and after the treatment show significant improvement (P< 0.01). If it is compared in between the two groups, the differences between the Sleep quality of PSQI scores for both groups before and after the treatment have statistical significance according to the t-test (P<0.01), suggesting that the treatment group is superior to the control group.On Fall asleep time of PSQI aspect, the Fall asleep time of PSQI scores for both groups before and after the treatment show significant improvement (P<0.05). If it is compared in between the two groups, the differences between Fall asleep time of PSQI scores for both groups before and after the treatment have no statistical significance according to the t-test (P>0.05), suggesting that the efficacy of both groups for Fall asleep time of PSQI scores are similar.On Sleep time of PSQI aspect, the Sleep time of PSQI scores for both groups before and after the treatment show significant improvement (P<0.05). If it is compared in between the two groups, the differences between Sleep time of PSQI scores for both groups before and after the treatment have no statistical significance according to the t-test (P>0.05), suggesting that the efficacy of both groups for Sleep time of PSQI scores are similar.On Sleep rate of PSQI aspect, the Sleep rate of PSQI scores for both groups before and after the treatment show significant improvement (P<0.01). If it is compared in between the two groups, the differences between the Sleep rate of PSQI scores for both groups before and after the treatment have statistical significance according to the t-test (P<0.01), suggesting that the treatment group is superior to the control group.On Sleep disorder of PSQI aspect, the Sleep disorder of PSQI scores for both groups before and after the treatment show significant improvement (P <0.01). If it is compared in between the two groups, the differences between the Sleep disorder of PSQI scores for both groups before and after the treatment have statistical significance according to the t-test (P<0.05), suggesting that the treatment group is superior to the control group.On Daytime dysfunction of PSQI aspect, the Daytime dysfunction of PSQI scores for both groups before and after the treatment show significant improvement (P<0.01). If it is compared in between the two groups, the differences between the Daytime dysfunction of PSQI scores for both groups before and after the treatment have statistical significance according to the t-test (P<0.01), suggesting that the treatment group is superior to the control group.②PSQI total scores of different observation time pointsAfter the first week of treatment, On PSQI total scores aspect, the PSQI total scores for both groups before and after the treatment show significant improvement (P<0.01). If it is compared in between the two groups, the differences between PSQI total scores for both groups before and after the treatment have no statistical significance according to the t-test (P>0.05), suggesting that the efficacy of both groups for PSQI total scores are similar.After four weeks of treatment, On PSQI total scores aspect, the PSQI total scores for both groups before and after the treatment show significant improvement (P<0.01). If it is compared in between the two groups, the differences between PSQI total scores for both groups before and after the treatment have no statistical significance according to the t-test (P<0.01), suggesting that the efficacy of both groups for PSQI total scores are similar. 2. HAMD scaleOn HAMD scores aspect, the HAMD scores for treatment group before and after the treatment show significant improvement (P<0.01). But the control group shows no change (P>0.05). If it is compared in between the two groups, the differences between the HAMD scores for both groups before and after the treatment have statistical significance according to the t-test (P<0.05), suggesting that the treatment group is superior to the control group.ConclusionThe research results suggest that both two methods have definite effect on the Climacteric Insomnia. The PSQI scores, the HAMD scores and the overall efficiency rate for treatment group show substantial improvement after the treatment and the differences have statistical significance. But the control group shows no change (P>0.05). According to the comparison among groups, the Sleep quality, the Sleep rate, the Sleep disorder and the Daytime dysfunction of PSQI of treatment group is superior to the control group. The others are similar. On HAMD scores and Total effective rate aspect, treatment group is superior to the control group. According to the experimental results above, it is assumed that the temporal the two methods for Climacteric Insomnia can significantly improve the sleep and Depression of patients. But the method of treatment group is a better choice. |
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