Objective:By random sampling, comparative analysis, on liver kidney and regulating complement of self-made Decoction for the treatment of liver and kidney yin deficiency type objective assessment of clinical effects of menopause syndrome, and try to observe its effect on long-term complications of menopause syndrome, discussion on self-made liver, kidney and regulating mechanism of nourishing Decoction for the treatment of Menopause Syndrome.Method:Collected in the outpatient clinics to Taiwan between may2011and march201360cases of syndrome of deficiency of liver and kidney in patients with Menopause Syndrome, randomly divided into treatment group and the control group two groups, each set of the30cases. Self-treatment group given liver, kidney and regulating nourishing soup, compared to Qi qijudihuang pills were treating a total of three months. Compare the two groups before and after treatment of TCM Symptom Score, improving kupperman score and compare the two groups before and after treatment with serum estradiol (e2), follicular stabbed hormone (fsh), luteinizing hormone (LH), fasting blood glucose (fbg), fasting Insulin (fins), total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL) levels.Results:1. Treatment of group96.7of the total efficiency, of which2cases of healing, a surge of20cases, effective in7cases,1cases of invalid; the control group,86.7per cent of efficient, cure1cases,17cases of bearing fruit, effective in8cases,4cases of invalid. Total efficiency comparison of differences between the two groups was statistically significant (p<0.05).2. After two groups of treatment is to reduce kupperman points compared with the treatment, the differences were statistically significant (p<0.05). After group therapy, hot flashes, insomnia, irritability, sweating, dizziness, fatigue, muscle, bone and joint pain, symptoms such as sexual difficulty kupperman integral is less than before treatment, the difference was statistically significant (p<0.05); the control group after treatment, insomnia, dizziness, fatigue fatigue, muscle pain and other symptoms of Bone and Joint kupperman integral is less than before treatment, the difference was statistically significant (p<0.05). After group therapy, hot flashes, irritability, Khan, sexual difficulty, and other symptoms kupperman integral than the control group after treatment of integral significantly reduced, the difference was statistically significant (p<0.05).3. After group therapy, hot sweats, insomnia, many dreams, upset mouth dry dry throat, five symptoms such as fever, soreness of the waist and the knees are more than85effective rate; the control group after treatment, the less the close, soreness of the waist and the knees to improve the effective rate above85.4. Two sets of treatment, FSH and1h are higher than before the treatment of significant drop, E2than before treatment significantly increased the differences were statistically significant (p<0.05). Between the two treatments before and after fsh, LH, E2levels were not significantly different (p>0.05).5.Before the TC levels after treatment group therapy in the treatment of decreased HDL levels were lower than before treatment significantly improved, the differences were statistically significant (p<0.05), TG, LDL levels and treatment of the former no significant differences (p>0.05). A control group before and after treatment with TC, TG, LDL, HDL levels were not significantly different (p>0.05). Comparison between the two groups, group TC levels than the control group after treatment decreased HDL levels compared with the control group markedly improved, the differences were statistically significant (p<0.05).6.FBG levels after treatment group therapy in the treatment of significant decline before, the difference was statistically significant (p<0.05), there is no significant difference between the fins level and treatment (p>0.05); the control group before and after treatment with fbg, fins level had not changed significantly (p>0.05).Conclusion:1. Self-made regulating and nourishing liver-kidney soups and Qi Ju Huang pill all could improve kupperman index of menopausal syndrome of yin deficiency of liver and kidney type integrals, Self-made regulating and nourishing liver-kidney soups was better on improving single symptomkupperman index, such as hot flashes, irritability, sweating, sexual intercourse difficult than Qi dihuang.2. Self-made regulating and nourishing liver-kidney soups and Qi qijudihuang pills could all improve FSH, LHand E2levels in patients with Menopause Syndrome of liver and kidney-yin deficiency type, but Self-made regulating and nourishing liver-kidney soups could improve the symptoms of yin deficiency of liver and kidney type of Menopause Syndrome better than Qi qijudihuang pill.3. Self-made regulating and nourishing liver-kidney soups can effectively improve glucose and lipid metabolism in patients with Menopause Syndrome of liver and kidney-yin deficiency type. For prevention of long-term complications of menopause syndrome, Self-made regulating and nourishing liver-kidney soups would be better than Qi qijudihuang pill. |