| Objective:To investigate the change on patients with functional premature ventricular contractions in clinical symptoms, premature ventricular contractions numbers, heart rate variability and quality of life before and after treatment, evaluate the effectiveness and safety of abdominal acupuncture on improving the clinical symptoms, reducing the numbers of premature ventricular contractions, regulating cardiac autonomic nervous function and improving the patient’s quality of life. And to provide therory basis for abdominal acupuncture in treating with functional premature ventricular contractions by discussing its mechanism.Methods:This study used a randomized controlled method, We divided the patients into a treatment group and a control group in a ratio of1:1. the treatment group as abdominal acupuncture treatment, the control group as minimal acupuncture points acupuncture treatment, the treating was every other day, three times a week,30minutes each time, The treatment process was12times. And followed up for one month after treatment. Observe the change on clinical symptoms, Palpitation number, Palpitation duration, premature ventricular contractions numbers, heart rate variability and quality of life. Explore the regularity of abdominal acupuncture acupoint selection on functional premature ventricular contractions patients, and monitor security indicators.Results:1.The comparison of comprehensive efficacy:After treatment, The total effective rate was64.6%%in abdominal acupuncture group, The total effective rate was13.3%in the controlled group, the difference between the two groups was significant (P<0.05), the comprehensive efficacy of abdominal acupuncture treatment on patients with premature ventricular contractions was better than the controlled group.2.The comparison of clinical symptoms efficacy:After the treatment and one month after the treatment, two groups of patients clinical symptom score decreased compared with before treatment (P<0.05). There also was significant difference between two groups (P<0.05). The total effective rate was87.1%in treatment group and43.3%in controlled group, There was significant difference between two groups (P<0.05).3. The comparison of Chinese single sympotom efficacy:After the treatment and one month after the treatment, seven single Chinese sympotoms core were reduced. In two groups, There were significantly difference compared with before treatment in treatment group (P<0.05). The palpitation and fatigue score were significantly difference compared with before treatment in the controlled group (P<0.05). The efficacy of palpitation, irritability, fatigue, shortness of breath and insomnia were significant difference between two groups, The treatment group has better efficacy in improving Chinese clinical syndrome.4.The extent of palpitation:After the treatment and one month after the treatment, The Palpitation score, Palpitations episodes per week and Palpitation duration were reduced. The treatment group in the different observation points were significant difference compared with before treatment (P<0.05). The Palpitation score and Palpitation duration were difference compared with before treatment in the controlled group at one month after the treatment (P<0.05). There were significant difference between two groups in the different observation points (P<0.05).5. The comparison of Chinese clinical symptoms immediately and obviously relieve:There were no significant difference in Chinese clinical symptoms immediately relieve betweent two groups (P>0.05). duration of symptoms is statistically significant between two groups. There were no significant difference in Chinese clinical symptoms obviously relieve betweent two groups. But significant difference in clinical symptoms obviously relieve points.6. The comparison of premature ventricular contractions:The premature ventricular contractions of24hours significant reduced after treatment in treatment group (P<0.05), the control group compared with before treatment no significant change (P>0.05). There was significant difference in the number of premature ventricular contractions reduced between two groups (P<0.05). the total effective rate of premature ventricular contractions was67.8%in treatment group and13.3%in control group. There was significant difference between two groups (P<0.05). abdominal acupuncture treatment reduce the number of premature ventricular contractions and the efficacy is better than minimal acupuncture points acupuncture treatment.7.The comparison of heart rate variability:before treatment, The SDNN、 SDANN、SDNNI、PNN50、HF、LF were lower than the normal reference values. rMSSD and LF/HF were higher than the normal reference values. The time domain indexes were increased after treatment. There were significant difference on SDNN、 SDANN、rMSSD、PNN50in treatment group compared with before treatment. But the control group have no difference compared with before treatment. On frequency domain indexes, The HF and LF were increased after treatment in treatment group, the change of HF have significant difference compared with before treatment (P<0.05). but the control group have no significant difference copmpared with before treatment (P>0.05). after treatment, the LF/HF was reduced both of two groups. The treatment group have difference compared with before treatment (P<0.05), but the control group have no. The comparison of two groups have no difference (P>0.05).8. The comparison of quality of life:After the treatment and one month after the treatment, the quality of life was improved both of two groups. The treatment group in every dimensions of quality of life score compared with before had significant difference (P<0.05). the control group in social function and health function compared with before had significant difference (P<0.05). There were significant difference on general healthurole physicals role emotional, mental health and change of health function between two groups (P<0.05).9. the regularity of abdominal acupuncture acupoint selection:by frequency statistics, the ZhongWan、XiaWan、QiHai、GuanYuan、ShuiFen、left ShuiFen pang、left QiPang、left QiXue were high frequence points of abdominal acupuncture acupoint, used frequency was100%. According to acupuncture points clustering and combined with the commonality and specific syndrome between different types patients, abdominal acupuncture acupoint selection has a certain regularity:Phlegm wet serious, add two sides of DaHeng; Shoulder joint pain, add HuaRouMen; deficiency serious, add right QiXue; Frequent Night urination, add two sides of ShuiDao; Abdominal gas impassability, add two sides of XiaFengShidian; Dry stool or constipation, add TianShu or left XiaFengShidian; neck discomfort or head discomfort caused by neck, add two sides of ShuangQu, mores erious, add JianLi.10. Security Comparison:In treatment group, two patients appeared small range subcutaneous ecchymosis, instruct patients with raw potato chips after topical scattered stasis can adhere to the treatment, at the time of before and after treatment and one month after treatment, two groups of patients were on present heart rate、blood pressure and other signs of abnormalities. In the process of treatment, two groups of patients have no Needlesickness、 infection、Broken needle and can’t stand pain related to acupuncture.Conclusion:1. Abdominal acupuncture treatment can significantly improve the Chinese clinical symptoms of functional premature ventricular contractions patients, reduce the times of palpitations episodes and shorten the duration of the palpitations.2. Abdominal acupuncture treatment can significantly reduce the number of premature ventricular contractions of patients, and the efficacy is better than minimal acupuncture points acupuncture treatment.3. Abdominal acupuncture treatment can improve the heart tate variability of functional premature ventricular contractions patients, and regulation of cardiac autonomic nerve function.4. Abdominal acupuncture treatment can significantly improve the quality of life in patients with functional premature ventricular contractions, especially on general health role physicaK role emotionaK mental health and change of health function.5. ZhongWan、XiaWan、QiHai、GuanYuan、ShuiFen、left ShuiFen pang、left QiPang、 left QiXue are basic points for functional premature ventricular contractions patients, On the basic points according to the disease and syndrome differentiation plus or minus points.6. Abdominal acupuncture therapy is safe, effective, and no significant side effects, It is worth further promote the use of clinical. |
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