Study On The Academic Thoughts And Clinical Experiences Of Professor Qiu Heming In Hemorrhagic Syndromes

This study has two parts. Part one aims at a general summary on the academic thoughts and clinical experiences of Professor Qiu Heming on hemorrhagic syndromes. With nearly half century’s medical practice, Professor Qiu developed profound academic achievements in medical research and got rich experiences in treating hemorrhagic syndrome.His academic achievements rooted deeply from classical works of Chinese traditional medicine and theories of other medical masters in history such as Canon of Huangdi, Liu Hejian, Zhu Danxi, Zhang Jingyue, and theory of warm disease school.During the clinical practice on hemorrhagic syndrome, Professor Qiu believes that fires act as important reasons for hemorrhagic syndromes. He always uses three energizer differentiation method and wei-qi-ying-xue methods to differentiate hemorrhagic syndrome besides ba-gang principles. Professor Qiu emphasize entirety conceptions in the differentiation process, he always takes syndromes and diseases together into differentiation. He always takes it carefully to balance the two sides of yin and yang during the treatment for hemorrhagic syndromes. He also give high praise to the treatise on hemorrhagic syndromes an famous classical medical work by Tang Rong-chuan who first established the four major hemostatic methods which are to stop bleeding, to dissipate coagulation, to cool down circulation and to reinforce sufficiency.Professor Qiu is very expert at applying basic principles of Chinese medicine in the complicated clinical problems. With his profound experiences of medical practice he developed many new theories and new methods for hemorrhagic syndromes. Professor Qiu creatively applied the principle about the liver’s holding blood in the treatment of idiopathic thrombocytopenic purpura (ITP). He found that ITP was caused by liver’s incapacity to hold blood, so he use methods of soothing liver, nourishing liver, pacifying liver and clearing liver to treat ITP to promote the liver’s blood holding ability and to decrease the damage of platelets. This method gets very good results in elevating platelets level.Professor Qiu believes that insufficiency of kidney and hemostasis are responsible for the development of multiple myeloma, so he created a herbal formula of Bushen Huoxue Fang to promote the curing efficacy for multiple myeloma. He also created an Yangyin Bushen formula for aplastic anemia (AA) with his accurate understanding about the focal pathological lesion in AA which is the yin deficiency of kidney. Professor Qiu believes that excessive pathogens and insufficient essences are both important in the development of leukemia, so he insists that expelling external pathogens and supplying inner insufficiencies play the same important roles in curing leukemia.The second part of this study is about the clinical and laboratory researches on multiple myeloma(MM) treated with bushen huoxue fang.This study applies random and control methods. About22Patients with MM were allotted into experiment group and control group, all the patients of the two groups were treated with the M2chemotherapy regimen for4to6cycles which lasted nearly half a year. The patients in experiment group were applied with oral decoction of bushen huoxue fang daily for21days per cycle lasting for half a year. At the end of treatment, all patients were tested on bone marrow cellularity, serial β2-microglobulin and lymphocytic subgroups including the regulatory T cells (CD4+CD25+Treg). The results show that the experiment group has higher CR rate, PR rate and effective rate than the control group but with no statistical significance. The serial β2-microglobulin level in experiment group is higher than that in control group with statistic significance. The lymphocyte analysis shows higher levels of CD4+T and CD4+CD25+Teg in experiment group than in control group with statistic significance. So it is concluded that bushen huoxue fang is effective in treating MM to reduce tumor burden and increasing CD4+T cells and decreasing regulatory T cells which means the immune function will be intensified.