Based On The Mathematical Statistics And Data Mining Method In Treatise On Febrile Disease Temperature Class All The Law Of Syndrome Differentiation Research

The purpose and significance of the study:Based on current "Treatise on Febrile Diseases" in treatment of, research and systematic syndrome differentiation rules of its rare in reports; secondly, ancient and modern medical records is one of the effective carrier of traditional Chinese prescription, the collection of clinical practice, traditional Chinese medicine prescription compatibility with addition and subtraction, application method and the classical theory of traditional Chinese medicine the essence of "Treatise on Febrile Diseases", to rule as the outline of ancient and modern Chinese medicine system study based on medical records, the involved in science, law, medicine, medicine, and so on documentary proof as the basis, focuses on "Treatise on the" temperature method in prescription and syndrome differentiation and treatment of disease-disease-Card--drug-quantity-effect correlation between syndrome differentiation and treatment, strengthening, and law and the internal mechanism of the regularity of TCM basic theory of explaining, inheritance and innovation, to guide the standardization, exploring the idea of evidence-based medicine and traditional Chinese medicine research, to provide the clinical application. For a particular disease curative effect evaluation and evidence for recommended levels, famous doctors and prescriptions research ideas and methodology, the reference for the development of new drugs and its compatibility with literature reference etc. has important significance. A limited range of doctoral study period collected in time, resources and information, based on the "Treatise on the" temperature method as the key link, and with reference to the "Treatise on the" class selection criteria, the final selection of "Treatise on Febrile Diseases" in10prescriptions for the "Treatise on the" representative temperature method class party, ancient and modern a case of "Treatise on the" temperature method of prescription and syndrome differentiation based on the law of.Research methods:This study first determines the prescription selected in the range of "Treatise on the"113party to temperature method as the main method of class10prescriptions, prescription drug addition and subtraction similarity is defined as100%. Secondly, through the preliminary screening, in the past on the "Treatise on the" works,"two continued medical case" as the representative of the Department of medical books, since the1911-2012journal literature collection, browse, sort,1751cases of "Treatise on the" relevant medicine temperature method class party literature into the case, and a preliminary screening database corresponding; third, through the establishment of strict entry criteria, exclusion criteria, the data processing method of (the case of structured data and unstructured data combined methods of consolidation, the corresponding increase in clinical medical evaluation and level of evidence fraction content analysis according to the research purpose), research methods and database structure design, in order to respect medical information as much as possible a comprehensive collection of medical record information, to meet after a one-time, objective, comprehensive records of original data, the next meet study a variety of research objective, multi-angle, multi-level requirements; Fourth, to medical prescription name clear for10Wenli method class party, patients and four diagnostic information, to meet the requirements of drug addition and subtraction complete similarity, the drug dose clearly expressed, efficacy clearly expressed, drug addition and subtraction method statement, drug norms, processing and usage instructions for establishment of medical evidence rating scale for the basic requirements,, excluding1554cases, the final selection of197clinical cases of high level test case evidence to recommend screening for two times to remove the database, data noise. Fifth, the197clinical cases of high level of evidence, carefully screened as core, establish "Treatise on the" temperature method class party case analysis database, including basic information (such as the source of medical records, medical records, the author published in literature, medical records, records the number, gender, age, etiology, description and classification of (West) the name of disease, the clinical effective Description Description Description, clinical cure, drug addition and subtraction rule description, prescription use pay attention to item (such as processing methods, decocting method, dosage, medication safety), classification of syndrome, symptoms, treatment, drug classification classification classification, and treatment principle, calcite, drug addition and subtraction, effective interpretation the number of recovery agent, agent, prescription, prescription dose, total dose average main symptom, syndrome type description, description of key drug ratio requirements, decocting law requirements, evaluation of curative effect, safety analysis of the target database, the use of data analysis and computer software for the corresponding treatment, especially through comparison and analysis, on the foundation of traditional Chinese medicine theory and clinical practice of interpretation, summarized, refined and summarized.Result:1) find out the "theory" clinical temperature method class party indications and drug addition and subtraction of typhoid, better guide clinical application; nature exploration temperature method.2) to establish EBM thought "Treatise on the" temperature method of clinical evidence from literature database.3) of principle-method-recipe-medicines application of standardization.4) guidelines for clinical diagnosis and treatment of prescription.5) to provide ideas for the Chinese medicine prescription drug development.6) for further study of classical prescription and later when the clinical application and provide the best evidence to provide methodological reference.Especially the "Treatise on the" temperature method as research target, research will effect of disease-disease-Card--drug-Volume-in the medical records of the correlation also rare in the reported medical records. Fourth, the ancient and modern literature, the modern idea of evidence-based medicine and medical evidence level concept, database development and data mining analysis, individual case analysis according to the level of evidence is also insufficient. So it is necessary to adopt new ideas and new methods to study temperature method class party. At the same time, through the analysis of ancient and modern literature, will also add, refine on "added later doctors prescription matrix treatise on the" temperature method, make up the "Treatise on the" does not provide the temperature inside the medicine treatment method.