Stroke Onset Of Clinical Characterization Of Correlation Analysis

Objective:Study on the correlation between the state in the two months prior to onset of stroke and state of stroke onset as well as the effects of syndrome factors and first symptoms on stroke short term prognoses. To explore the clinical characters of the stroke onset process and to provide evidence-based advice for making early clinical decisions.Methods:The research was divided into two parts. And the first parts is about the correlation between transient symptoms in two months before stroke onset and first symptoms. The second part is about the correlation between the state in the two months prior to onset of stroke. And effects of first syndrome factors and first symptoms on stroke short term prognoses is also explored.Part1:We extracted the clinical information of3227cases according with the inclusive criteria, and analyzed the first symptoms and first symptomatic flocks. The frequency statistics method, association rules and Sequence were applied.Part2:(1) Data of demographic characteristics, individual history and life style and transient symptoms in two months before stroke onset were seen as the state prior to onset of stroke. The correlations between state prior to onset of stroke and initial syndrome factors/disease severity were explored using chi-square test and Logistic regression analysis.(2) Data of demographic characteristics, individual history and life style, first symptoms, initial syndrome factors and NIHSS score were seen as state of stroke onset.The correlation between state of stroke onset and short prognoses were analyzed by adopting chi-square test, Logistic regression analysis as the analytical tool.Results:Part1:Among those symptoms, hemiplegia was the tiptop of1720cases, accounted for53.3%. Dizziness was just less than hemiplegia, accounted for20.08%. It was found that there were mainly two forms of symptomatic flocks. Some flocks were the combinations of stroke primary symptoms, others were combinations related to dizziness. Visual rotation and dizziness were most common among two combinations of first symptoms. Nausea and vomiting were often accompanied by dizziness.Part2:(1)Both mono-factor analysis and Logistic regression analysis showed transient speaks unclear was associated with the severity of stroke and was a dependent of influential factors of the severity of stroke.(2) Logistic regression analysis showed hemiplegia, hemianesthesia, coronary heart disease were dependent of influential factors of wind syndrome. Coronary heart disease was dependent of influential factors of fire syndrome. Transient hemianesthesia and coronary heart disease were dependent of influential factors of blood stasis syndrome. The qi deficiency syndrome influence factor, hemianesthesia, female, hemiplegia were dependent of influential factors of qi deficiency syndrome. Transient hemianesthesia, facial numbness and coronary heart disease were dependent of influential factors of yin deficiency syndrome.(3) Mono-factor analysis showed:the prognosis of14th day of stroke influence factors, NIHSS scores grade, dizziness, qi deficiency, transient speaks unclear were significant different. Logistic regression analysis showed dizziness, NIHSS scores grade were dependent of influential factors of short term prognosis of stroke.Conclusion:(1)The first symptoms and first symptomatic flocks of stroke are complex with low specifity except the primary symptoms. Attention should be paid not only to main primary symptoms but also rare symptoms and symptoms of non-specific.(2) Similarity and consistency of transient symptoms in two months before stroke onset and first symptoms of stroke onset indicated process of stroke was continuous.(3) The state prior to onset of stroke and the syndromes and severity of stroke onset were correlated. Symptoms before stroke onset and past history should be attended to and treate.(4) State of stroke onset was correlated with prognosis of14th day and prognosis of21th day. Dizziness may be a indicator for favorable prognosis in stroke and qi deficiency may indicate a bad prognosis.